Konety Badrinath R, Sharp Victoria J, Raut Hrishikesh, Williams Richard D
University of Iowa Department of Urology, Iowa City, Iowa, USA.
Urology. 2008 Mar;71(3):511-4. doi: 10.1016/j.urology.2007.09.019.
The issue of prostate cancer screening and management is likely to assume greater importance with progressive aging of the population. Because there are no currently established guidelines for screening and management of prostate cancer in elderly men (older than 75 years), a multidisciplinary panel was convened to develop consensus recommendations.
The panel consisted of experts in urology, internal medicine/geriatrics, medical oncology, radiation oncology, family practice, law, patient advocacy and physician assistants. Four internationally known experts on prostate cancer served as external advisors. Relevant literature was reviewed and consensus was developed based on expert opinion, given the lack of level I evidence regarding most aspects of prostate cancer diagnosis and management in men older than 75 years of age.
On the basis of the opinions of the expert panel, recommendations for screening and management of prostate cancer in elderly men older than 75 years of age was developed. In general, there was support for using greater discretion in screening for prostate cancer in elderly men. The lack of adequate patient education tools to facilitate discussion with patients was recognized. There was also agreement on the need for greater and renewed patient counseling regarding benefits and risks of prostate cancer screening beyond age 75.
It is possible to build consensus around a standardized approach to prostate cancer screening and management in older men. Promulgation of such consensus recommendations and their widespread adoption may help engender a tailored approach to managing prostate cancer in older men, thereby decreasing health care costs and morbidity while limiting unnecessary therapy.
随着人口的不断老龄化,前列腺癌筛查与管理问题可能会变得越发重要。由于目前尚无针对老年男性(75岁以上)前列腺癌筛查与管理的既定指南,因此召集了一个多学科小组以制定共识性建议。
该小组由泌尿外科、内科/老年医学、医学肿瘤学、放射肿瘤学、家庭医疗、法律、患者权益倡导及医师助理等领域的专家组成。四位国际知名的前列腺癌专家担任外部顾问。鉴于缺乏关于75岁以上男性前列腺癌诊断和管理大多数方面的一级证据,对相关文献进行了综述并基于专家意见达成了共识。
根据专家小组的意见,制定了75岁以上老年男性前列腺癌筛查与管理的建议。总体而言,对于在老年男性前列腺癌筛查中更加谨慎行事存在支持意见。认识到缺乏足够的患者教育工具来促进与患者的讨论。对于75岁以上前列腺癌筛查的益处和风险,也一致认为需要加强并重新开展患者咨询。
围绕老年男性前列腺癌筛查与管理的标准化方法达成共识是可能的。颁布此类共识性建议并广泛采用可能有助于形成针对老年男性前列腺癌的个性化管理方法,从而降低医疗成本和发病率,同时限制不必要的治疗。