Tambo Yuichi, Fujimura Masaki, Yasui Masahide, Kasahara Kazuo, Nakatsumi Yasuto, Nakao Shinji
Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine.
Intern Med. 2008;47(6):527-31. doi: 10.2169/internalmedicine.47.0644. Epub 2008 Mar 17.
A 72 year-old man. He was diagnosed with rheumatoid arthritis in 2002. In January 2005 he noted productive cough and fever; he was diagnosed as eosinophilic pneumonia (EP). We discontinued administration of bucillamine and methotrexate and started to treat with oral prednisolone 30 mg daily. To rule out drug-induced EP, prednisolone was tapered by 10 mg per week. Consolidation occurred in the right lower lobe when prednisolone was decreased to 5 mg daily. After increasing the dose of prednisolone to 30 mg daily again, consolidation was promptly resolved. It was considered to be important to rule out drug-induced EP.
一名72岁男性。他于2002年被诊断为类风湿性关节炎。2005年1月，他出现咳痰和发热症状；被诊断为嗜酸性粒细胞性肺炎（EP）。我们停用了布西拉明和甲氨蝶呤，并开始每日口服30毫克泼尼松龙进行治疗。为排除药物性EP，泼尼松龙每周递减10毫克。当泼尼松龙减至每日5毫克时，右下叶出现实变。再次将泼尼松龙剂量增至每日30毫克后，实变迅速消退。排除药物性EP被认为很重要。
