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排除药物性嗜酸性粒细胞性肺炎的类风湿关节炎相关嗜酸性粒细胞性肺炎。

Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.

作者信息

Tambo Yuichi, Fujimura Masaki, Yasui Masahide, Kasahara Kazuo, Nakatsumi Yasuto, Nakao Shinji

机构信息

Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine.

出版信息

Intern Med. 2008;47(6):527-31. doi: 10.2169/internalmedicine.47.0644. Epub 2008 Mar 17.

Abstract

A 72 year-old man. He was diagnosed with rheumatoid arthritis in 2002. In January 2005 he noted productive cough and fever; he was diagnosed as eosinophilic pneumonia (EP). We discontinued administration of bucillamine and methotrexate and started to treat with oral prednisolone 30 mg daily. To rule out drug-induced EP, prednisolone was tapered by 10 mg per week. Consolidation occurred in the right lower lobe when prednisolone was decreased to 5 mg daily. After increasing the dose of prednisolone to 30 mg daily again, consolidation was promptly resolved. It was considered to be important to rule out drug-induced EP.

摘要

一名72岁男性。他于2002年被诊断为类风湿性关节炎。2005年1月,他出现咳痰和发热症状;被诊断为嗜酸性粒细胞性肺炎(EP)。我们停用了布西拉明和甲氨蝶呤,并开始每日口服30毫克泼尼松龙进行治疗。为排除药物性EP,泼尼松龙每周递减10毫克。当泼尼松龙减至每日5毫克时,右下叶出现实变。再次将泼尼松龙剂量增至每日30毫克后,实变迅速消退。排除药物性EP被认为很重要。

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