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微创短节段后路内固定联合磷酸钙球囊后凸成形术治疗爆裂性及严重压缩性腰椎骨折

Minimal invasive short posterior instrumentation plus balloon kyphoplasty with calcium phosphate for burst and severe compression lumbar fractures.

作者信息

Korovessis Panagiotis, Hadjipavlou Alexander, Repantis Thomas

机构信息

General Hospital Agios Andreas, Patras, Greece.

出版信息

Spine (Phila Pa 1976). 2008 Mar 15;33(6):658-67. doi: 10.1097/BRS.0b013e318166e0bb.

Abstract

STUDY DESIGN

Prospective consecutive series.

OBJECTIVE

To evaluate the efficacy of minimal invasive surgery for acute lumbar fractures by means of balloon kyphoplasty with calcium phosphate plus segmental short posterior instrumented fusion.

SUMMARY OF BACKGROUND DATA

In the surgical treatment of lumbar fractures with short pedicle screw instrumentation, the failure to support the anterior spinal column often results in loss of correction. Transpedicular augmentation techniques with bone and bone substitutes have been attempted whereas kyphoplasty has been increasingly used to augment fractured vertebral body.

METHODS

Eighteen consecutive patients with an average age of 64 +/- 15 years, who sustained lumbar (L1-L4) burst and severe compression fracture were included in this prospective study. On admission, 2 (11%) of 18 patients had incomplete neurologic impairment. All patients underwent bilateral balloon kyphoplasty with calcium phosphate bone cement to reduce segmental kyphosis and restore vertebral body height and segmental pedicle screw instrumentation and fusion. Gardner kyphosis angle, anterior (AVBHr) and posterior vertebral body height ratio (PVBHr), and spinal canal encroachment (SCE) were calculated before to after surgery. VAS and SF-36 were used to evaluate functional outcome.

RESULTS

All patients were operated within 24 hours after admission and were followed for an average 22 months (17-28 months) after index surgery. Operating time and blood loss averaged 45 minutes and 70 mL, respectively. VAS and SF-36 (role physical and bodily pain domains) were significantly improved after surgery. Both patients with incomplete neurologic lesions recovered, whereas no neurologic deterioration was observed in any case. Segmental kyphosis improved from an average preoperative kyphosis of 16 to 2 degrees after surgery (P < 0.000). AVBHr improved from an average before surgery 0.57 to 0.87 (P < 0.000) after surgery, whereas PVBHr improved from 0.93 before surgery to 0.98 (P < 0.05) after surgery. SCE was reduced from an average 25% before surgery to 19% (P < 0.07) after surgery. Bone cement leakage was observed anteriorly to the fractured vertebral body or to the adjacent superior disc in 4 patients without clinical sequelae, whereas 3 pedicle screws were malpositioned medially to the pedicle in 3 patients without neurologic impairment or associated complaints. Posterolateral radiologic fusion was achieved within 6 to 8 months after index operation. There was no instrumentation failure or loss of sagittal curve and vertebral height correction.

CONCLUSION

Balloon kyphoplasty with calcium phosphate cement combined with posterior segmental short minimal invasive fixation for fresh burst and severe compression lumbar fractures provided excellent immediate reduction of post-traumatic segmental kyphosis with simultaneous reduction of spinal canal encroachment and restoration of vertebral body height in the fracture level.

摘要

研究设计

前瞻性连续病例系列。

目的

通过使用磷酸钙联合节段性短节段后路器械融合的球囊后凸成形术,评估微创手术治疗急性腰椎骨折的疗效。

背景资料总结

在采用短椎弓根螺钉器械治疗腰椎骨折时,未能支撑前柱常导致矫正丢失。已尝试使用骨和骨替代物的经椎弓根强化技术,而后凸成形术越来越多地用于强化骨折椎体。

方法

本前瞻性研究纳入了18例平均年龄为64±15岁的连续患者,这些患者均遭受腰椎(L1-L4)爆裂性骨折和严重压缩性骨折。入院时,18例患者中有2例(11%)存在不完全神经功能障碍。所有患者均接受双侧球囊后凸成形术,使用磷酸钙骨水泥以减少节段性后凸畸形并恢复椎体高度,以及节段性椎弓根螺钉器械固定和融合。计算术前和术后的加德纳后凸角、椎体前(AVBHr)和后椎体高度比(PVBHr)以及椎管侵占率(SCE)。使用视觉模拟评分法(VAS)和健康调查简表(SF-36)评估功能结局。

结果

所有患者均在入院后24小时内接受手术,术后平均随访22个月(17-28个月)。手术时间和失血量平均分别为45分钟和70毫升。术后VAS和SF-36(角色生理和身体疼痛领域)显著改善。2例不完全神经损伤患者均康复,且未观察到任何神经功能恶化情况。节段性后凸畸形从术前平均16度改善至术后2度(P<0.000)。术后AVBHr从术前平均0.57改善至0.87(P<0.000),而PVBHr从术前0.93改善至术后0.98(P<0.05)。SCE从术前平均25%降至术后19%(P<0.07)。4例患者在骨折椎体前方或相邻上位椎间盘处观察到骨水泥渗漏,但无临床后遗症,3例患者有3枚椎弓根螺钉向椎弓根内侧移位,但无神经功能障碍或相关主诉。在初次手术后6至8个月实现了后外侧影像学融合。未出现器械失败或矢状面曲线及椎体高度矫正丢失的情况。

结论

对于新鲜的爆裂性和严重压缩性腰椎骨折,采用磷酸钙骨水泥球囊后凸成形术联合后路节段性短节段微创固定,能立即显著减轻创伤后节段性后凸畸形,同时减少椎管侵占并恢复骨折节段的椎体高度。

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