[头痛与系统性红斑狼疮：患病率及相关情况]

[Headache and systemic lupus erythematosus: prevalence and associated conditions].

作者信息

Bettero Raphael Guimarães, Rahal Mansur Youssef, Barboza Joaquim Spadoni, Skare Thelma L

机构信息

Faculdade Evangélica do Paraná, Serviço de Reumatologia do Hospital Universitário Evangélico de Curitiba, Curitiba PR, Brasil.

出版信息

Arq Neuropsiquiatr. 2007 Dec;65(4B):1196-9. doi: 10.1590/s0004-282x2007000700020.

DOI:10.1590/s0004-282x2007000700020

PMID:18345429

Abstract

OBJECTIVE

To study the prevalence of headache in patients with systemic lupus erythematosus (SLE) and normal population as well as associated conditions.

METHOD

Forty nine SLE patients and 50 controls were analyzed for presence of headaches (tensional and migraine). In the SLE group, we studied the occurrence of Raynaud, teleangiectasis, cutaneous vasculitis, convulsions and antiphospholipid antibodies.

RESULTS

Among SLE patients, 42 had headaches (85.7%), 29 with migraine and 13 tensional; on the control group, 28 had headaches (57.1%), 18 migraine and 10 tension type with p=0.0026 for migraine. In SLE patients we did not find any association between migraine and Raynaud (p=0.34), teleangiectasis (p=0.77), cutaneous vasculitis (p=0.63), seizures (p=0.13), aCl IgG (p=0.45), IgM (=0.07) and LAC (p=0.59).

CONCLUSION

Migraine is more prevalent in the SLE population. However, it has no relationship with Raynaud, teleangiectasis, seizures, cutaneous vasculitis and antiphospholipid antibodies.

摘要

目的

研究系统性红斑狼疮（SLE）患者和正常人群中头痛的患病率及其相关情况。

方法

对49例SLE患者和50例对照者进行头痛（紧张性头痛和偏头痛）情况分析。在SLE组中，我们研究了雷诺现象、毛细血管扩张、皮肤血管炎、惊厥和抗磷脂抗体的发生情况。

结果

SLE患者中，42例有头痛（85.7%），其中29例为偏头痛，13例为紧张性头痛；对照组中，28例有头痛（57.1%），其中18例为偏头痛，10例为紧张型头痛，偏头痛的p值为0.0026。在SLE患者中，我们未发现偏头痛与雷诺现象（p=0.34）、毛细血管扩张（p=0.77）、皮肤血管炎（p=0.63）、惊厥（p=0.13）、抗心磷脂抗体IgG（p=0.45）、IgM（p=0.07）和狼疮抗凝物（p=0.59）之间存在任何关联。