Padial A, Morales V, Armario-Hita J C, Ingunza J L, Fernández-Vozmediano J M
Servicio de Dermatología, Hospital Universitario de Puerto Real, Universidad de Cádiz, España.
Actas Dermosifiliogr. 2008 Mar;99(2):134-7.
We report a case of a 15-year-old boy with hyperkeratotic lesions that were linear or striated on the palms and nummular on the soles. He was the only family member known to be affected, suggesting that the condition could be attributed to a de novo mutation or the recessive form of keratoderma palmoplantaris striata, described by Degos as chronic idiopathic acrokeratosis. The lesions did not improve with topical treatments (keratolytic agents, emollients, or corticosteroids) or oral retinoids. We observed that scratching of the affected areas was the main reason for deterioration of the lesions.
我们报告一例15岁男孩，其手掌出现线状或条纹状的角化过度性皮损，足底出现钱币状皮损。他是已知唯一受影响的家庭成员，这表明该病可能归因于新发突变或掌跖条纹状角化病的隐性形式，德戈斯将其描述为慢性特发性肢端角化病。局部治疗（角质剥脱剂、润肤剂或皮质类固醇）或口服维甲酸类药物均不能改善皮损。我们观察到，搔抓患区是皮损恶化的主要原因。
