Schlossbauer T, Hellerhoff K, Reiser M
Institut für Klinische Radiologe, Klinikum Grosshadern der Ludwig-Maximilians-Universität München, München.
Radiologe. 2008 Apr;48(4):351-7. doi: 10.1007/s00117-008-1638-5.
The aim of this study is to give an overview on early detection of breast cancer in patients with an increased risk of breast cancer. Sensitivities and diagnostic accuracies of breast MRI, mammography and ultrasound were compared.
A systematic literature search of the past 3 years was performed. Studies which compared breast imaging modalities and used image-guided biopsy results as standard of reference were included. Patients included had to have had an increased lifetime risk for breast cancer (>15%).
Regarding sensitivity and diagnostic accuracy, breast MRI performed best in comparison to the other modalities within this collective of patients. Sensitivities ranged from 71-100%, 0-78%, and 13-65%, for MRI, mammography, and ultrasound, respectively
Breast MRI is a well established tool for screening in patients at high risk for developing breast cancer and is a valuable supplement to mammography and ultrasound within this selected cohort of patients.
本研究旨在概述乳腺癌高危患者的早期检测情况。比较了乳腺磁共振成像（MRI）、乳腺X线摄影和超声的敏感性及诊断准确性。
对过去3年进行了系统的文献检索。纳入了比较乳腺成像方式并将影像引导活检结果用作参考标准的研究。纳入的患者终身患乳腺癌风险必须增加（>15%）。
就敏感性和诊断准确性而言，在该组患者中，乳腺MRI与其他方式相比表现最佳。MRI、乳腺X线摄影和超声的敏感性分别为71 - 100%、0 - 78%和13 - 65%。
乳腺MRI是筛查乳腺癌高危患者的成熟工具，在该特定患者队列中，它是乳腺X线摄影和超声的宝贵补充。
