Ritz Thomas, Rosenfield David, Meuret Alicia E, Bobb Carol, Steptoe Andrew
Department of Psychology, Southern Methodist University, Dallas, TX 75205, USA.
Ann Behav Med. 2008 Feb;35(1):97-104. doi: 10.1007/s12160-007-9014-7. Epub 2008 Feb 16.
Hyperventilation symptoms are among the sensations asthma patients tend to report during exacerbations of their disease. However, little is known about their importance for the patients' perceived well-being.
We therefore studied the association of reported hyperventilation symptoms (Asthma Symptom Checklist) with perceived physical and mental health (36-item Short-form Health Survey) in a sample of primary care asthma patients (N = 190). We also studied the potential role of perceived control of asthma (Perceived Control of Asthma Questionnaire) in mediating any association between these variables.
In hierarchical multiple regression analyses controlling for demographics, asthma severity, and other asthma symptoms (obstruction, congestion, panic-fear, irritation, and fatigue), hyperventilation symptoms were significantly associated with both physical and mental health status. This association was partially mediated by perceived control of asthma.
It is possible that hypocapnia creates symptoms that asthma patients cannot control by using their antiasthmatic medication, thus compromising their perceived control over the management of their asthma, and consequently their perceived health. Behavioral interventions should address the problem of hyperventilation in asthma.
过度通气症状是哮喘患者在疾病发作期间倾向于报告的感觉之一。然而,对于这些症状对患者幸福感的重要性知之甚少。
因此,我们在一组初级保健哮喘患者样本(N = 190)中,研究了报告的过度通气症状(哮喘症状清单)与感知到的身心健康(36项简短健康调查问卷)之间的关联。我们还研究了哮喘自我控制感(哮喘自我控制问卷)在调节这些变量之间关联中的潜在作用。
在控制了人口统计学因素、哮喘严重程度和其他哮喘症状(阻塞、充血、惊恐-恐惧、刺激和疲劳)的分层多元回归分析中,过度通气症状与身心健康状况均显著相关。这种关联部分由哮喘自我控制感介导。
低碳酸血症可能产生哮喘患者无法通过使用抗哮喘药物控制的症状,从而损害他们对哮喘管理的自我控制感,进而影响他们的感知健康。行为干预应解决哮喘中的过度通气问题。