倒提壶中的吡咯里西啶生物碱。

Pyrrolizidine alkaloids from Cynoglossum furcatum.

作者信息

Ravi S, Ravikumar R, Lakshmanan A J

机构信息

Research & Development, Hindustan Photo Films Ltd, Udhagamandalam, The Nilgiris, Tamilnadu, India.

出版信息

J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):349-54. doi: 10.1080/10286020701833503.

DOI:10.1080/10286020701833503

PMID:18348059

Abstract

Two new pyrrolizidine alkaloids have been isolated from the roots of Cynoglossum furcatum. On the basis of chemical and spectroscopic evidence, structures of the compounds have been elucidated. They are lactodine (3), a monoster alkaloid and viridinatine (4), a pyrrolizidine diester alkaloid. The structure of lactodine is elucidated as 9-O-(-)lactyl heliotridine and viridinatine as 7-O-(-)viridifloryl echinatine.

摘要

从倒提壶的根部分离出了两种新的吡咯里西啶生物碱。基于化学和光谱证据，阐明了这些化合物的结构。它们是单酯生物碱乳毒定（3）和吡咯里西啶二酯生物碱绿毛倒提壶碱（4）。乳毒定的结构被阐明为9-O-(-)乳酰天芥菜定，绿毛倒提壶碱的结构为7-O-(-)绿毛倒提壶酰刺凌德草碱。