Serpe Michael J, Rivera Monica, Kersey Farrell R, Clark Robert L, Craig Stephen L
Department of Chemistry, Department of Mechanical Engineering and Materials Science, and Center for Biologically Inspired Materials and Material Systems, Duke University, Durham, North Carolina 27708-0346, USA.
Langmuir. 2008 May 6;24(9):4738-42. doi: 10.1021/la703418w. Epub 2008 Mar 19.
Polymer bridging between surfaces plays an important role in a range of fundamental processes in the material and life sciences. Bridges formed by main-chain reversible polymers differ from their covalent analogs in that they can dynamically adjust their size and shape in response to external stimuli and have the potential to reform following bond scission. In this work, the time and distance dependence of main-chain reversible polymer bridge formation are studied using an atomic force microscope. The bridging process was studied using single-molecule force spectroscopy, and its dependence on the distance between surfaces and equilibration time was probed. The number of bridges formed decreases as the gap width increases, from approximately 2 bridges per 14 s equilibration at separations of 5-15 nm to approximately 0.5 bridges per 14 s equilibration at separations of 35-45 nm. The kinetics of bridge formation appear to be slightly faster at smaller separations.
表面之间的聚合物桥接在材料科学和生命科学的一系列基础过程中起着重要作用。主链可逆聚合物形成的桥与其共价类似物不同，因为它们可以根据外部刺激动态调整其大小和形状，并且在键断裂后有重新形成的潜力。在这项工作中，使用原子力显微镜研究了主链可逆聚合物桥形成的时间和距离依赖性。使用单分子力谱研究了桥接过程，并探究了其对表面之间距离和平衡时间的依赖性。形成的桥的数量随着间隙宽度的增加而减少，从在5 - 15纳米间距下每14秒平衡形成约2个桥，到在35 - 45纳米间距下每14秒平衡形成约0.5个桥。在较小的间距下，桥形成的动力学似乎略快一些。
