Psychiatric University Hospital Zurich, Research Group on Substance Use Disorders, Selnaustrasse 9, 8002 Zurich, Switzerland.
Harm Reduct J. 2008 Mar 18;5:10. doi: 10.1186/1477-7517-5-10.
Smoking rates in methadone-maintained patients are almost three times higher than in the general population and remain elevated and stable. Due to the various negative health effects of smoking, nicotine dependence contributes to the high mortality in this patient group. The purpose of the current study was to investigate Swiss methadone and buprenorphine-maintained patients' willingness to stop smoking and to clarify further smoking cessation procedures.
Substance abuse history, nicotine dependence, and readiness to stop smoking were assessed in a sample of 103 opiate-dependent patients in the metropolitan area of Zurich, Switzerland. Patients were asked to document their smoking patterns and readiness to quit.
Only a small number of patients were willing to quit smoking cigarettes (10.7%) and, even though bupropione or nicotine replacement therapy was included in the fixed daily treatment care, only one patient received nicotine replacement therapy for smoking cessation. A diagnosis of depression in patients' clinical records was associated with readiness to stop smoking. No significant associations were found between readiness to quit smoking and age, methadone treatment characteristics, and presence of co-dependencies.
The current prescription level of best medicine for nicotine dependence in Swiss methadone and buprenorphine-maintained patients is far from adequate. Possible explanations and treatment-relevant implications are discussed.
美沙酮维持治疗患者的吸烟率几乎是普通人群的三倍，且这一比率仍然居高不下且保持稳定。由于吸烟对健康有诸多负面影响，尼古丁依赖导致该患者群体的死亡率居高不下。本研究旨在调查瑞士美沙酮和丁丙诺啡维持治疗患者的戒烟意愿，并阐明进一步的戒烟程序。
在瑞士苏黎世大都市区的 103 名阿片类药物依赖患者的样本中，评估了药物滥用史、尼古丁依赖和戒烟意愿。要求患者记录自己的吸烟模式和戒烟意愿。
只有少数患者愿意戒烟（10.7%），尽管丁丙诺啡或尼古丁替代疗法被纳入固定的每日治疗护理中，但只有一名患者接受尼古丁替代疗法来戒烟。患者临床记录中的抑郁诊断与戒烟意愿相关。在准备戒烟方面，与年龄、美沙酮治疗特征以及共病的存在之间没有发现显著的相关性。
瑞士美沙酮和丁丙诺啡维持治疗患者目前对尼古丁依赖的最佳药物治疗处方水平远远不够。讨论了可能的解释和治疗相关的影响。
