Krahn Lois E, Miller Bernard W, Bergstrom Larry R
Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA.
J Clin Sleep Med. 2008 Feb 15;4(1):64-5.
Patients with insomnia may develop suicidal ideation; however, we know of no reports of suicidal ideation associated with obstructive sleep apnea. We report on a 74-year-old man who presented to his primary care physician with excessive daytime sleepiness, poor quality nocturnal sleep, depressed mood, and suicidal ideation with active suicide plans. An emergency outpatient psychiatry consultation was arranged. The patient declined psychiatric hospitalization. He agreed to a trial of continuous positive airway pressure, using a self-titrating machine, followed by an urgent sleep study. Polysomnography revealed an apnea hypopneaindex of 64, arousal index of 91 and minimum oxygen saturation of 65%. The patient's sleep and excessive daytime sleepiness responded to nCPAP. The patient declined antidepressant medication but had excellent adherence to nCPAP. Suicidal ideation and depression resolved promptly and at 4-month followup were in remission. Further studies examining the relationship among untreated obstructive sleep apnea, depression, and suicidal ideation are warranted.
失眠患者可能会出现自杀意念;然而,我们尚未知晓有与阻塞性睡眠呼吸暂停相关的自杀意念报告。我们报告了一名74岁男性,他因日间过度嗜睡、夜间睡眠质量差、情绪低落以及带有积极自杀计划的自杀意念而就诊于其初级保健医生。安排了一次紧急门诊精神科会诊。患者拒绝住院接受精神科治疗。他同意试用持续气道正压通气,使用自动调压设备,随后进行紧急睡眠研究。多导睡眠图显示呼吸暂停低通气指数为64,觉醒指数为91,最低血氧饱和度为65%。患者的睡眠及日间过度嗜睡症状对无创持续气道正压通气治疗有反应。患者拒绝服用抗抑郁药物,但对无创持续气道正压通气治疗依从性良好。自杀意念和抑郁症状迅速缓解,在4个月的随访中处于缓解状态。有必要进一步研究未经治疗的阻塞性睡眠呼吸暂停、抑郁和自杀意念之间的关系。