Kovacević Maja, Tamarut Tomislav, Jonjić Nives, Braut Alen, Kovacević Miljenko
Department of Dental Pathology, School of Dentistry, Medical Faculty, University of Rijeka, Rijeka, Croatia.
Aust Endod J. 2008 Apr;34(1):12-8. doi: 10.1111/j.1747-4477.2008.00120.x.
The purpose of the study was to histologically analyse transition from pulpitis to periapical periodontitis on dog's teeth. Pulps of mandibular premolars (37 roots) were exposed using a low-speed handpiece. Teeth were left open to the oral environment for 20, 35, 50 and 65 days. After the experimental period animals were sacrificed. Undemineralised teeth with surrounding bone, embedded in methylmetacrylate, were prepared for standard histological analysis. All teeth with pulpitis (five roots), regardless of the experimental period, had acute serose periapical periodontitis. All teeth (15 roots) with partial pulp necrosis had subacute periapical periodontitis. Teeth with complete pulp necrosis (19 roots) had chronic periapical periodontitis and in one case suppurative apical periodontitis. The condition of the pulp correlates with the histopathological findings of periapical tissue in the open types of pulp infection. Acute periapical periodontitis begins during pulpitis and can occur before 20 days of pulp exposure in the dog.
本研究的目的是对犬牙从牙髓炎到根尖周炎的转变进行组织学分析。使用低速手机暴露下颌前磨牙的牙髓（37个牙根）。将牙齿暴露于口腔环境20、35、50和65天。实验期结束后处死动物。将带有周围骨组织的未脱矿牙齿包埋于甲基丙烯酸甲酯中，制备用于标准组织学分析的样本。所有患有牙髓炎的牙齿（5个牙根），无论实验期长短，均患有急性浆液性根尖周炎。所有患有部分牙髓坏死的牙齿（15个牙根）均患有亚急性根尖周炎。患有完全牙髓坏死的牙齿（19个牙根）患有慢性根尖周炎，在1例中为化脓性根尖周炎。在开放性牙髓感染类型中，牙髓状况与根尖周组织的组织病理学发现相关。急性根尖周炎在牙髓炎期间开始，在犬牙髓暴露20天之前即可发生。
