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1例色素性紫癜性苔藓样皮炎对补骨脂素紫外线A光化学疗法(PUVA)治疗反应显著。

A case of Schamberg's disease responding dramatically to PUVA treatment.

作者信息

Seckin Dilek, Yazici Zuleyha, Senol Asli, Demircay Zeynep

机构信息

Department of Dermatology, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Photodermatol Photoimmunol Photomed. 2008 Apr;24(2):95-6. doi: 10.1111/j.1600-0781.2008.00337.x.

Abstract

Pigmented purpuric dermatoses are a group of chronic, recurrent disorders characterized by purpuric lesions mainly involving the lower extremities. Their etiology is unknown. Treatment options are limited and none of them have proven benefit. Phototherapy has been reported to be effective in a small number of patients in the literature. We present a case of Schamberg's disease showing a dramatic response to psoralen plus ultraviolet A therapy and discuss the current therapeutic options focusing mainly on phototherapy. We believe that phototherapy is a valuable alternative, especially for patients with long-standing and widespread pigmented purpuric dermatitis.

摘要

色素性紫癜性皮病是一组慢性复发性疾病,其特征为紫癜性皮损,主要累及下肢。其病因不明。治疗选择有限,且均未证实有疗效。据文献报道,光疗对少数患者有效。我们报告1例进行性色素性紫癜性皮病对补骨脂素加紫外线A疗法有显著反应的病例,并主要围绕光疗讨论当前的治疗选择。我们认为光疗是一种有价值的替代疗法,尤其适用于长期存在且广泛分布的色素性紫癜性皮炎患者。

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