Seishima M, Shibuya Y, Suzuki S, Arakawa C
Department of Dermatology, Ogaki Municipal Hospital, Ogaki City, Japan.
Clin Exp Dermatol. 2008 Aug;33(5):588-90. doi: 10.1111/j.1365-2230.2008.02713.x. Epub 2008 Mar 18.
We report a patient with acute heart failure due to human parvovirus B19 infection. The patient was a 36-year-old man with polyarthralgia, fatigue and swelling of his upper eyelids and all four limbs. These symptoms disappeared, but 5 days after the first consultation, the patient presented with severe exertional dyspnoea, chest pain and swelling of his whole body. Erythema was observed on the skin of hands, fingers and abdomen. Pleural and pericardial effusion, ascites and hepatosplenomegaly were detected. Laboratory examination showed positive results for anti-human parvovirus B19 IgM and B19 DNA in the serum. A diagnosis of acute heart failure by pericarditis caused by B19 was made. This case report suggests that B19 should be considered as a cause of acute heart failure through acute pericarditis.
我们报告了一例因人类细小病毒B19感染导致急性心力衰竭的患者。该患者为一名36岁男性，有多关节痛、疲劳以及上眼睑和四肢肿胀的症状。这些症状消失了，但在首次就诊5天后，患者出现严重劳力性呼吸困难、胸痛和全身肿胀。在手、手指和腹部皮肤观察到红斑。检测发现有胸腔和心包积液、腹水以及肝脾肿大。实验室检查显示血清中抗人类细小病毒B19 IgM和B19 DNA呈阳性。诊断为由B19引起的心包炎导致的急性心力衰竭。该病例报告提示，B19应被视为通过急性心包炎导致急性心力衰竭的一个病因。
