Hosszú E, Sallai A
Semmelweis Orvostudományi Egyetem II. Gyermekklinika, Budapest.
Orv Hetil. 1997 Mar 9;138(10):611-13.
The pathogenicity of the human parvovirus B19 has been disclosed in the last two decades. Different syndromes (erythema infectiosum or hydrops fetalis) can be produced by this virus as well as aplastic crisis in patients with haemolytic anaemia. It is a common infection both in adults and in children. The frequency of joint symptoms in erythema infectiosum is about 8% in childhood but tenfold of it in the adults. However, the arthropathy could be the only symptom without constitutional complains or rash. The joint problems used to be solved after some weeks in most cases but occasionally they could keep for some months or years. The disease is thought to be rheumatoid arthritis if the possibility of a parvovirus B19 infection has not been considered. In this paper the authors present a case report of a 14 years old boy with fever of unknown origin, skin eruptions and arthritis. On that connection, they discussed the recent knowledge about the human parvovirus B19 and refer to its importance in differential diagnosis of joint problems.
人类细小病毒B19的致病性在过去二十年中已被揭示。这种病毒可引发不同的综合征（传染性红斑或胎儿水肿），以及溶血性贫血患者的再生障碍危象。它在成人和儿童中都是常见感染。传染性红斑中关节症状的发生率在儿童期约为8%，而在成人中则是其十倍。然而，关节病可能是唯一的症状，没有全身不适或皮疹。大多数情况下，关节问题在几周后会自行缓解，但偶尔也可能持续数月或数年。如果没有考虑到细小病毒B19感染的可能性，这种疾病可能会被误诊为类风湿性关节炎。在本文中，作者报告了一例14岁男孩的病例，该男孩有不明原因发热、皮疹和关节炎。就此，他们讨论了关于人类细小病毒B19的最新知识，并提及了其在关节问题鉴别诊断中的重要性。
