Wu H L, Li S F, Zeng B W, Yu R Q
Department of Chemistry and Chemical Engineering, Hunan University, Changsha.
Yao Xue Xue Bao. 1991;26(3):214-8.
Based on the brief discussion of error propagation in multivariate calibration and analysis, the flexible tolerance simplex method (FTSM) was applied to analyze vitamin B1, B2, B6 and niacinamide simultaneously. The results obtained were comparatively satisfactory both in precision and in accuracy. The average recoveries of vitamin B1, B2, B6 and niacinamide were 99.8 +/- 0.9% (CV), 100. 1 +/- 0.8% (CV), 100.2 +/- 2.1% (CV) and 100.1 +/- 0.7% (CV) respectively. All these show that FTSM, with calibration matrix K calculated from K = ASCST (CSCST)-1, is one of the most efficient procedures for improving accuracy, especially when there are interactions between variables and the problem is ill-conditioned.
基于对多元校准与分析中误差传播的简要讨论，采用灵活容差单纯形法（FTSM）同时分析维生素B1、B2、B6和烟酰胺。所得结果在精密度和准确度方面都比较令人满意。维生素B1、B2、B6和烟酰胺的平均回收率分别为99.8±0.9%（变异系数）、100.1±0.8%（变异系数）、100.2±2.1%（变异系数）和100.1±0.7%（变异系数）。所有这些都表明，通过K = ASCST (CSCST)-1计算校准矩阵K的FTSM是提高准确度的最有效方法之一，尤其是当变量之间存在相互作用且问题病态时。
