Lucotte G, Berriche S, Petit M C, Burckel A, Turpin J C
Laboratoire d'Anthropologie Physique, Collège de France, Paris.
Rev Neurol (Paris). 1991;147(8-9):602-4.
The presymptomatic diagnosis of Huntington chorea (HC) by genic amplification (PCR: polymerase chain reaction) of a DNA G8 sequence containing a polymorphic HindIII site was tested in a particular HC genealogy. The advantage of this method are discussed.
通过对含有多态性HindIII位点的DNA G8序列进行基因扩增（PCR：聚合酶链反应），对亨廷顿舞蹈病（HC）进行症状前诊断，并在一个特定的HC系谱中进行了测试。讨论了该方法的优势。
