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[焦虑症患者的躯体状况]

[Somatic conditions in patients suffering from anxiety disorders].

作者信息

Pascual Juan Carlos, Castaño Juan, Espluga Nuria, Díaz Belén, García-Ribera Carlos, Bulbena Antonio

机构信息

Instituto de Atención Psiquiátrica, IAPS, Hospital del Mar, Departamento de Psiquiatría, Universidad Autónoma de Barcelona, Barcelona, España.

出版信息

Med Clin (Barc). 2008 Mar 8;130(8):281-5. doi: 10.1157/13116589.

Abstract

BACKGROUND AND OBJECTIVE

Several studies have shown a higher prevalence of somatic illnesses in patients with anxiety disorders, especially cardiopathy, pneumopathy, digestive diseases and cephalea. The aim of this study was to investigate the comorbidity between anxiety disorders and medical illnesses in a group of patients with anxiety disorders compared with patients without psychiatric disorder attended at a primary care clinic and with psychiatric patients without anxiety pathology.

PATIENTS AND METHOD

Retrospective case-control study comparing 3 groups of patients paired by age and sex. The group of patients with anxiety disorders included 130 patients diagnosed by DSM-IV as panic disorders with/without agoraphobia and agoraphobia without panic attacks. There were 2 control groups: 150 patients without psychiatric disorder attended at primary care and 130 psychiatric patients without anxiety disorder attended at a psychiatric service.

RESULTS

Patients with anxiety disorders showed higher risk of medical illnesses than patient without anxiety. Multivariate statistical logistic regression analysis showed that patients with anxiety presented 4.2-fold increase in the risk of cephalea, 3.9 of cardiopathy, 3.8 of osteomuscular disorder and 2-fold increase in the risk of digestive diseases.

CONCLUSIONS

Patients with anxiety disorders presented higher risk of somatic illness. Similar physiopathology and genetic etiology could explain this association.

摘要

背景与目的

多项研究表明,焦虑症患者中躯体疾病的患病率较高,尤其是心脏病、肺病、消化系统疾病和头痛。本研究的目的是调查一组焦虑症患者与在初级保健诊所就诊的无精神障碍患者以及无焦虑病理的精神科患者相比,焦虑症与内科疾病之间的共病情况。

患者与方法

采用回顾性病例对照研究,比较按年龄和性别配对的3组患者。焦虑症患者组包括130例根据《精神疾病诊断与统计手册》第四版诊断为伴有/不伴有广场恐惧症的惊恐障碍以及无惊恐发作的广场恐惧症患者。有2个对照组:150例在初级保健机构就诊的无精神障碍患者和130例在精神科就诊的无焦虑症的精神科患者。

结果

焦虑症患者患内科疾病的风险高于无焦虑症患者。多变量统计逻辑回归分析显示,焦虑症患者患头痛的风险增加4.2倍,患心脏病的风险增加3.9倍,患骨肌肉疾病的风险增加3.8倍,患消化系统疾病的风险增加2倍。

结论

焦虑症患者患躯体疾病的风险较高。相似的生理病理学和遗传病因可以解释这种关联。

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