Hualde Olascoaga J, Molins Castiella T, Souto Hernández S, Becerril Moreno F, Yoldi Petri M E, Sagaseta de Ilurdoz M, Molina Garicano J
Unidad de Oncohematología Infantil, Servicio de Pediatría, Hospital Virgen del Camino, Pamplona, Spain.
An Pediatr (Barc). 2008 Mar;68(3):282-5. doi: 10.1157/13116711.
Reversible posterior leukoencephalopathy syndrome is a clinical-radiological phenomenon associated with headache, vomiting, lethargy, visual disturbances and seizures, concomitant with radiological abnormalities predominantly within posterior cerebral white matter due to cerebral edema. There are multiple triggers as acute hypertension, cancer, hematological disease, renal pathology, red cells transfusions and different drugs. We present two patients with reversible posterior leukoencephalopathy under treatment for acute lymphoblastic leukemia because of the probable association with vinca alkaloids.
可逆性后部白质脑病综合征是一种临床-放射学现象，与头痛、呕吐、嗜睡、视觉障碍和癫痫发作相关，同时伴有由于脑水肿导致的主要位于大脑后部白质的放射学异常。有多种诱因，如急性高血压、癌症、血液系统疾病、肾脏病变、红细胞输血及不同药物。我们报告了两名正在接受急性淋巴细胞白血病治疗的可逆性后部白质脑病患者，病因可能与长春花生物碱有关。
