Boutouyrie P
Université Paris-Descartes, Faculté de Médecine René Descartes, INSERM, UMR872, 12, rue Ecole de Médecine 75006 Paris, France.
Diabetes Metab. 2008 Feb;34 Suppl 1:S21-6. doi: 10.1016/S1262-3636(08)70099-5.
Arterial stiffness is now included in the guidelines of the European Society of Hypertension. In this paper, we review the evidence for the predictive value of arterial stiffness. More than 11 longitudinal trials have proven the predictive value of aortic stiffness measured through carotid to femoral pulse wave velocity, beyond and above classical risk factors. Such evidence is scarcer for central pressure and local arterial stiffness. If we add this evidence to the easiness of performing such measure, carotid to femoral pulse wave velocity is the reference technique for assessing arterial stiffness. Its place in the investigation of patients remains to be precised.
动脉僵硬度现已被纳入欧洲高血压学会的指南。在本文中,我们回顾了关于动脉僵硬度预测价值的证据。超过11项纵向试验已经证明,通过颈股脉搏波速度测量的主动脉僵硬度具有预测价值,其预测价值超过了经典危险因素。关于中心血压和局部动脉僵硬度的此类证据则较为稀少。如果将这一证据与进行此类测量的简便性相结合,颈股脉搏波速度是评估动脉僵硬度的参考技术。其在患者检查中的地位仍有待明确。