Halabe Bucay Alberto
Department of Pediatrics, Hospital Angeles Lomas, Huixquilucan, Mexico.
Exp Hematol. 2008 Jun;36(6):752-4. doi: 10.1016/j.exphem.2008.02.001. Epub 2008 Mar 20.
Lipotropins are peptides that act as hormones that are released from a common precursor together with other physiologically important peptides; their function is to mobilize the lipids that are stored in adipocytes as an energy reserve. This review will explain the existing scientific evidence on the action of lipotropins in adipocytes and, specifically, when these lipotropins activate bone marrow adipocytes to function as hematopoietic factors and suggest the potential therapeutic use of lipotropins based on these effects.
促脂素是一类作为激素发挥作用的肽,它们与其他具有重要生理功能的肽一同从共同前体中释放出来;其功能是动员储存在脂肪细胞中的脂质作为能量储备。本综述将阐述关于促脂素在脂肪细胞中作用的现有科学证据,特别是当这些促脂素激活骨髓脂肪细胞以发挥造血因子功能时的情况,并基于这些作用提出促脂素潜在的治疗用途。