• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

促脂素作为造血因子的作用及其潜在的治疗用途。

The role of lipotropins as hematopoietic factors and their potential therapeutic use.

作者信息

Halabe Bucay Alberto

机构信息

Department of Pediatrics, Hospital Angeles Lomas, Huixquilucan, Mexico.

出版信息

Exp Hematol. 2008 Jun;36(6):752-4. doi: 10.1016/j.exphem.2008.02.001. Epub 2008 Mar 20.

DOI:10.1016/j.exphem.2008.02.001
PMID:18358591
Abstract

Lipotropins are peptides that act as hormones that are released from a common precursor together with other physiologically important peptides; their function is to mobilize the lipids that are stored in adipocytes as an energy reserve. This review will explain the existing scientific evidence on the action of lipotropins in adipocytes and, specifically, when these lipotropins activate bone marrow adipocytes to function as hematopoietic factors and suggest the potential therapeutic use of lipotropins based on these effects.

摘要

促脂素是一类作为激素发挥作用的肽,它们与其他具有重要生理功能的肽一同从共同前体中释放出来;其功能是动员储存在脂肪细胞中的脂质作为能量储备。本综述将阐述关于促脂素在脂肪细胞中作用的现有科学证据,特别是当这些促脂素激活骨髓脂肪细胞以发挥造血因子功能时的情况,并基于这些作用提出促脂素潜在的治疗用途。

相似文献

1
The role of lipotropins as hematopoietic factors and their potential therapeutic use.促脂素作为造血因子的作用及其潜在的治疗用途。
Exp Hematol. 2008 Jun;36(6):752-4. doi: 10.1016/j.exphem.2008.02.001. Epub 2008 Mar 20.
2
Human bone marrow adipocytes block granulopoiesis through neuropilin-1-induced granulocyte colony-stimulating factor inhibition.人骨髓脂肪细胞通过神经纤毛蛋白-1诱导的粒细胞集落刺激因子抑制来阻断粒细胞生成。
Stem Cells. 2008 Jun;26(6):1556-64. doi: 10.1634/stemcells.2008-0068. Epub 2008 Apr 3.
3
[Endorphins, lipotropins, corticotropins and related peptides].
Lille Med. 1978 Dec;23(10):733-9.
4
Bone marrow adipocytes support dexamethasone-induced osteoclast differentiation.骨髓脂肪细胞支持地塞米松诱导的破骨细胞分化。
Biochem Biophys Res Commun. 2009 May 15;382(4):780-4. doi: 10.1016/j.bbrc.2009.03.111. Epub 2009 Mar 24.
5
[Endorphins and lipotropins: relevant combined action].[内啡肽与促脂解素:相关联合作用]
Rev Invest Clin. 1989 Oct-Dec;41(4):389-90.
6
[Cell therapy for inherited diseases of the hematopoietic system].[造血系统遗传性疾病的细胞治疗]
C R Biol. 2007 Jun-Jul;330(6-7):538-42. doi: 10.1016/j.crvi.2007.04.003. Epub 2007 May 15.
7
[Pituitary lipotropins (LPH)].
Union Med Can. 1973 Apr;102(4):890-8.
8
[Bone marrow examination of inherited diseases in children].
Ann Biol Clin (Paris). 2007 Sep-Oct;65(5):483-503.
9
Blood cells. Part one--Bone marrow.血细胞。第一部分——骨髓。
Nurs Times. 2005;101(40):28-9.
10
Hematologic effects of androgens revisited: an alternative therapy in various hematologic conditions.
Semin Hematol. 1994 Apr;31(2):134-45.

引用本文的文献

1
ACTH promotes chondrogenic nodule formation and induces transient elevations in intracellular calcium in rat bone marrow cell cultures via MC2-R signaling.ACTH 通过 MC2-R 信号促进软骨结节形成,并在大鼠骨髓细胞培养物中诱导细胞内钙的短暂升高。
Cell Tissue Res. 2013 May;352(2):413-25. doi: 10.1007/s00441-013-1561-6. Epub 2013 Jan 29.