Waters Sandra J, Riordan Paul A, Keefe Francis J, Lefebvre John C
Department of Psychology, College of Behavioral and Social Sciences, North Carolina Central University, Durham, NC 27707, USA.
J Pain Symptom Manage. 2008 Jul;36(1):69-78. doi: 10.1016/j.jpainsymman.2007.08.015. Epub 2008 Mar 20.
This study used Ward's minimum variance hierarchical cluster analysis to identify homogeneous subgroups of rheumatoid arthritis patients suffering from chronic pain who exhibited similar pain behavior patterns during a videotaped behavior sample. Ninety-two rheumatoid arthritis patients were divided into two samples. Six motor pain behaviors were examined: guarding, bracing, active rubbing, rigidity, grimacing, and sighing. The cluster analysis procedure identified four similar subgroups in Samples 1 and 2. The first subgroup exhibited low levels of all pain behaviors. The second subgroup exhibited a high level of guarding and low levels of other pain behaviors. The third subgroup exhibited high levels of guarding and rigidity and low levels of other pain behaviors. The fourth subgroup exhibited high levels of guarding and active rubbing and low levels of other pain behaviors. Sample 1 contained a fifth subgroup that exhibited a high level of active rubbing and low levels of other pain measures. The results of this study suggest that there are homogeneous subgroups within rheumatoid arthritis patient populations who differ in the motor pain behaviors they exhibit.
本研究采用沃德最小方差层次聚类分析，以识别患有慢性疼痛的类风湿关节炎患者的同质亚组，这些患者在一段录像行为样本中表现出相似的疼痛行为模式。92名类风湿关节炎患者被分为两个样本。研究了六种运动性疼痛行为：保护动作、支撑动作、主动摩擦、僵硬、做鬼脸和叹息。聚类分析程序在样本1和样本2中识别出四个相似的亚组。第一个亚组所有疼痛行为水平较低。第二个亚组保护动作水平高，其他疼痛行为水平低。第三个亚组保护动作和僵硬水平高，其他疼痛行为水平低。第四个亚组保护动作和主动摩擦水平高，其他疼痛行为水平低。样本1包含第五个亚组，该亚组主动摩擦水平高，其他疼痛指标水平低。本研究结果表明，类风湿关节炎患者群体中存在同质亚组，他们表现出的运动性疼痛行为有所不同。
