Dopamine receptors in the rat thymus.

Radioreceptor assay and autoradiographic techniques with 3H-SCH 23390 as a ligand were used to characterize pharmacologically and to localize anatomically dopamine D-1 receptor sites in sections of rat thymus. 3H-SCH 23390 was specifically bound to sections of rat thymus in a manner consistent with the labeling of D-1 receptor sites. Autoradiography demonstrated the accumulation of 3H-SCH 23390 binding sites in the cortex of the thymus rather than in corpuscles.