用于啮齿动物肿瘤体内和体外多模态图像配准的固定装置。
Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors.
作者信息
Christian Nicolas, Lee John A, Bol Anne, De Bast Marc, Gallez Bernard, Grégoire Vincent
机构信息
Center for Molecular Imaging and Experimental Radiotherapy, Université Catholique de Louvain, Brussels, Belgium.
出版信息
Radiother Oncol. 2008 Apr;87(1):147-51. doi: 10.1016/j.radonc.2008.02.016. Epub 2008 Mar 24.
Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiography) registration of mouse tumors. The registration accuracy assessed by calculating the average minimal distance between two skew lines was in the order of 0.2-0.3 mm.
生物图像引导放射治疗要求正电子发射断层显像（PET）能准确识别肿瘤内具有生物学相关性的亚体积。在此框架下，研发了一种固定装置，用于研究小鼠肿瘤的多影像（计算机断层扫描（CT）、显微磁共振成像（micro-MRI）、显微正电子发射断层显像（micro-PET）和放射自显影）配准。通过计算两条异面直线之间的平均最小距离评估的配准精度约为0.2 - 0.3毫米。
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