Ther Clin Risk Manag. 2006 Dec;2(4):347-54. doi: 10.2147/tcrm.2006.2.4.347.
Sensitization to the house dust mite (Dermataphagoides pteronyssinus) (HDM) is the most common risk factor associated with the development of asthma in adults and children. The effectiveness of HDM control measures in the treatment of asthma is not yet proven. The strategies for control for avoidance depend on our understanding of the biology of the HDM. The evidence suggests a favorable effect of transferring allergic asthmatic children to naturally low dust mite environments, such as at altitude or in hospital, but little to suggest that this can be replicated in general practice by simple practical measures such as mattress covers. However, a recent multi-allergen reduction approach has suggested benefits may be achievable. HDM densities tend to be high in warm, humid conditions in the home, which may be modified by external factors, such as ventilation. However, ventilation control to reduce indoor humidity has had inconsistent effects on dust mite levels and asthma. The challenge is to further refine the interventions in large placebo-controlled trials such that clinical outcomes may be more easily demonstrated.
对屋尘螨（Dermatophagoides pteronyssinus）的致敏是与成人和儿童哮喘发展相关的最常见危险因素。控制屋尘螨措施在哮喘治疗中的有效性尚未得到证实。避免接触的控制策略取决于我们对屋尘螨生物学的理解。有证据表明，将过敏的哮喘儿童转移到自然灰尘螨含量低的环境中（如高海拔或医院），效果良好，但很少有证据表明，在一般实践中，通过床垫罩等简单的实际措施可以复制这种效果。然而，最近的多过敏原减少方法表明，可能可以实现获益。家中温暖、潮湿的环境中屋尘螨密度往往较高，这可能会受到外部因素（如通风）的影响。然而，通风控制以降低室内湿度对尘螨水平和哮喘的影响并不一致。挑战在于进一步在大型安慰剂对照试验中细化干预措施，以便更轻松地展示临床结果。
