伴有假性梅格斯综合征的子宫平滑肌瘤，酷似卵巢癌。
Uterine leiomyoma with associated pseudo-Meigs syndrome mimicking ovarian carcinoma.
作者信息
Landrum Lisa M, Rutledge Teresa L, Osunkoya Adeboye O, Mannel Robert
机构信息
Department of Obstetrics and Gynecology, 920 Stanton L. Young Boulevard, Oklahoma City, OK 73104, USA.
出版信息
J Okla State Med Assoc. 2008 Feb;101(2):38-9.
BACKGROUND
Uterine leiomyoma are commonly diagnosed in women of reproductive age. However, these benign tumors may present with clinical signs and symptoms that are consistent with ovarian carcinoma.
CASE
A 47-year-old gravida 0 presented with a large pelvic mass, ascites, bilateral pleural effusions, and an elevated CA 125 worrisome for ovarian carcinoma. Exploratory laparotomy revealed a 20,120 g pelvic mass, with 2 L ascites, and pelvic and periaortic lymphadenopathy. Final pathology was consistent with a benign giant leiomyoma. Postoperative course was complicated by reaccumulation of pleural effusion requiring therapeutic thoracentesis and diuretics. Patient had return to full activity with 50 pound weight loss at 8 weeks after surgery.
CONCLUSION
Elevated CA 125 levels and ascites are often associated with ovarian carcinoma, but it is also important to keep benign processes in the differential diagnosis when considering malignancy.
背景
子宫平滑肌瘤在育龄女性中很常见。然而，这些良性肿瘤可能出现与卵巢癌一致的临床体征和症状。
病例
一名47岁未孕女性出现盆腔巨大肿块、腹水、双侧胸腔积液，CA 125升高，令人担心患有卵巢癌。剖腹探查发现盆腔有一个20120克的肿块，伴有2升腹水以及盆腔和腹主动脉旁淋巴结病。最终病理结果与良性巨大平滑肌瘤一致。术后病程因胸腔积液再次积聚而复杂化，需要进行治疗性胸腔穿刺术和使用利尿剂。患者术后8周体重减轻50磅，恢复了完全活动能力。
结论
CA 125水平升高和腹水常与卵巢癌相关，但在考虑恶性肿瘤时，将良性病变纳入鉴别诊断也很重要。
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