Sanches-Silva Ana, Pastorelli Sarah, Cruz José M, Simoneau Catherine, Castanheira Isabel, Paseiro-Losada Perfecto
Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Pharmacy, University of Santiago de Compostela, E-15782 Spain.
J Agric Food Chem. 2008 Apr 23;56(8):2722-6. doi: 10.1021/jf703786e. Epub 2008 Mar 25.
The aim of the present work was to develop a rapid multimethod for the analysis of six photoinitiators (PIs) in powdered milk and to study the migration of these PIs from LDPE packaging into powdered milk. The optimized HPLC-DAD method showed high correlation coefficients (>0.9999) over a concentration range of 0.1-10.9 mg/L. The kinetics of migration of the photoinitiators from LDPE packaging into powdered milk were determined at different temperatures. The key parameters of migration phenomena (diffusion and partition coefficients) were determined. The diffusion coefficients at 5 degrees C ranged between 8.4 x 10(-12) (for ITX) and 5.1 x 10(-10) (for benzophenone) and those at 40 degrees C between 5.9 x 10(-10) (for ITX) and 6.1 x 10(-9) (for Irgacure 184). The diffusion coefficients of the six model migrants under study increased with temperature and showed a good Arrhenius relationship between 5 and 40 degrees C.
本研究的目的是开发一种快速多方法，用于分析奶粉中的六种光引发剂（PIs），并研究这些光引发剂从低密度聚乙烯（LDPE）包装迁移到奶粉中的情况。优化后的高效液相色谱-二极管阵列检测（HPLC-DAD）方法在0.1-10.9 mg/L的浓度范围内显示出高相关系数（>0.9999）。在不同温度下测定了光引发剂从LDPE包装迁移到奶粉中的动力学。确定了迁移现象的关键参数（扩散系数和分配系数）。5℃时的扩散系数范围为8.4×10⁻¹²（对于ITX）至5.1×10⁻¹⁰（对于二苯甲酮），40℃时的扩散系数范围为5.9×10⁻¹⁰（对于ITX）至6.1×10⁻⁹（对于Irgacure 184）。所研究的六种模型迁移物的扩散系数随温度升高而增加，并且在5至40℃之间呈现出良好的阿仑尼乌斯关系。
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