Lery L, Ducomet P, Trabaud M A
Institut Pasteur de Lyon.
C R Seances Soc Biol Fil. 1991;185(4):231-7.
Tetanus vaccine activity without mineral adjuvant (Polan T) has been measured in a population of aged people (36 females and 11 males-mean age = 80.18 years). Titrations by hemagglutination of sensitized turkey red cells are performed before and after primo-immunization and first booster. This research gives knowledges regarding to the antitetanus response in elderly, regarding to the efficiency of the Polan T vaccine in this population uneasy to immunize and regarding to the quality of the simple and cheap assay for antitetanus antibodies titration.
在老年人群体(36名女性和11名男性,平均年龄 = 80.18岁)中测量了不含矿物佐剂的破伤风疫苗(波兰T型)的活性。在初次免疫和首次加强免疫之前及之后,通过致敏火鸡红细胞血凝试验进行滴定。这项研究提供了关于老年人破伤风抗体反应、波兰T型疫苗在这个难以免疫的人群中的有效性以及破伤风抗体滴定的简单廉价检测方法质量的知识。