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[丝素蛋白作为组织工程生物材料的研究进展]

[Recent progress on silk fibroin as tissue engineering biomaterials].

作者信息

Wang Hongxin, Li Min

机构信息

College of Life Sciences, Fujian Normal University, Fuzhou Fujian, 350108, P.R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Feb;22(2):192-5.

Abstract

OBJECTIVE

To summarize the latest developments in silk fibroin as biomaterials and its applications in tissue engineering.

METHODS

The recent original literature on silk fibroin as biomaterials were extensively reviewed, illustrating the properties and applications of silk fibroin biomaterials in tissue engineering.

RESULTS

Silk fibroin as biomaterials had good biocompatibility and degradability. It supported the cell adhesion differentiation and growth. It was used for artificial ligament, vessel, bone, nerve and so on. After modification, silk fibroin could be extensively used in tissue engineering.

CONCLUSION

Silk fibroin is a good biomaterial, whichhas a great potential applications in tissue engineering.

摘要

目的

总结丝素蛋白作为生物材料的最新进展及其在组织工程中的应用。

方法

广泛综述了近期关于丝素蛋白作为生物材料的原始文献,阐述了丝素蛋白生物材料在组织工程中的特性和应用。

结果

丝素蛋白作为生物材料具有良好的生物相容性和可降解性。它支持细胞黏附、分化和生长。它被用于人工韧带、血管、骨骼、神经等。经过修饰后,丝素蛋白可广泛应用于组织工程。

结论

丝素蛋白是一种良好的生物材料,在组织工程中具有巨大的潜在应用价值。

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