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肾癌消融治疗:适应证与患者选择

Kidney cancer ablative therapy: indications and patient selection.

作者信息

Lehman Daniel S, Landman Jaime

出版信息

Curr Urol Rep. 2008 Jan;9(1):34-43. doi: 10.1007/s11934-008-0008-1.

DOI:10.1007/s11934-008-0008-1
PMID:18366972
Abstract

The increased application of radiographic imaging has paralleled a simultaneous increase in the detection of incidental and asymptomatic renal neoplasms. The reference standard for treating small renal tumors includes open and laparoscopic partial nephrectomy. The primary objectives of ablative renal procedures are to duplicate the excellent oncologic outcomes of partial nephrectomy while decreasing patient morbidity and shortening hospitalization and overall convalescence. Ablation, with cryotherapy or radiofrequency probes, offers the advantages of minimally invasive surgery, but with a significantly lower complication rate than laparoscopic partial nephrectomy. Ablation now represents a major change in surgical thinking as tumors are ablated and left in situ. This article reviews the status of the two ablative modalities currently available for clinical application, cryoablation and radiofrequency ablation.

摘要

放射成像应用的增加与偶然发现的无症状肾肿瘤检测数量的同时增加是并行的。治疗小肾肿瘤的参考标准包括开放和腹腔镜下部分肾切除术。肾消融手术的主要目标是在降低患者发病率、缩短住院时间和总体康复时间的同时,复制部分肾切除术出色的肿瘤学治疗效果。使用冷冻疗法或射频探头进行消融具有微创手术的优势,但其并发症发生率明显低于腹腔镜下部分肾切除术。由于肿瘤被消融并留在原位,消融现在代表了手术思维的重大转变。本文综述了目前可用于临床应用的两种消融方式——冷冻消融和射频消融的现状。

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Kidney cancer ablative therapy: indications and patient selection.肾癌消融治疗:适应证与患者选择
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The Role of Ablation and Minimally Invasive Techniques in the Management of Small Renal Masses.消融和微创技术在小肾肿瘤治疗中的作用。
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引用本文的文献

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Robotic-assisted laparoscopic cryo-partial nephrectomy: a novel technique using cryoablation in lieu of hilar clamping in a porcine model.机器人辅助腹腔镜冷冻部分肾切除术:一种在猪模型中使用冷冻消融替代肾门阻断的新技术。
J Robot Surg. 2010 Sep;4(3):191-6. doi: 10.1007/s11701-010-0211-1. Epub 2010 Aug 21.
2
Renal cryoablation of small renal masses: a Korea University experience.小肾肿瘤的肾冷冻消融术:韩国大学的经验
Korean J Urol. 2015 Feb;56(2):117-24. doi: 10.4111/kju.2015.56.2.117. Epub 2015 Feb 2.
3
A matched-cohort comparison of laparoscopic renal cryoablation using ultra-thin cryoprobes with open partial nephrectomy for the treatment of small renal cell carcinoma.

本文引用的文献

1
Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumours.临床T1a期肾肿瘤部分肾切除术与射频消融术的中期比较
BJU Int. 2007 Aug;100(2):287-90. doi: 10.1111/j.1464-410X.2007.06937.x.
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Is radiofrequency ablation safe for solitary kidneys?射频消融术对孤立肾安全吗?
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3
Laparoscopic cryoablation for small renal masses: three-year follow-up.腹腔镜下小肾肿瘤冷冻消融术:三年随访
超微冷冻探针腹腔镜肾冷冻消融术与开放性部分肾切除术治疗小肾细胞癌的配对队列比较。
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Enhancing renal masses with zero net growth during active surveillance.在主动监测期间使肾肿块在净生长为零的情况下增大
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The impact of ischemia time during open nephron sparing surgery on solitary kidneys: a multi-institutional study.开放保留肾单位手术中缺血时间对孤立肾的影响:一项多机构研究。
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Update on the epidemiology and biology of renal cortical neoplasms.肾皮质肿瘤的流行病学与生物学最新进展
J Endourol. 2006 Dec;20(12):975-85. doi: 10.1089/end.2006.20.975.
8
Energy ablative techniques for treatment of small renal tumors.用于治疗小肾肿瘤的能量消融技术。
Curr Opin Urol. 2006 Sep;16(5):321-6. doi: 10.1097/01.mou.0000240302.11379.5b.
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Experiences in US-guided percutaneous radiofrequency ablation of 44 renal tumors in 31 patients: analysis of predictors for complications and technical success.
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Trends in the operative management of renal tumors over a 14-year period.14年间肾肿瘤手术治疗的趋势
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