Schaeffer David F, Rusnak Conrad H, Amson Bradley J
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Am J Surg. 2008 May;195(5):565-9; discussion 569. doi: 10.1016/j.amjsurg.2008.01.003.
The prevalence of obesity in Canada is increasing, therefore, it has become imminently important to treat these patients in a timely manner.
A total of 120 consecutive patients who underwent a laparoscopic Roux-en-Y gastric bypass procedure (2004 to 2006), with a mean postoperative follow-up period of 19 months, were divided into 2 chronologic groups and analyzed retrospectively.
The overall postoperative excess weight loss was 78.1% (SD, 14.3%) from the time of inclusion into the study preoperatively (average wait time, 21 mo) to 12 months postoperatively. No preoperative weight loss was recorded. A surgeon-dependent learning curve was shown with a decrease in surgical time as well as surgery-related complications. Obesity-associated comorbidities decreased whereas quality of life increased.
Despite a structured multidisciplinary approach to alter lifestyle and daily caloric intake preoperatively, only laparoscopic Roux-en-Y gastric bypass showed effective weight loss and reduced associated comorbidities.
加拿大肥胖症的患病率正在上升，因此，及时治疗这些患者变得迫在眉睫。
共有120例连续接受腹腔镜Roux-en-Y胃旁路手术的患者（2004年至2006年），术后平均随访期为19个月，分为两个时间组并进行回顾性分析。
从术前纳入研究时（平均等待时间，21个月）到术后12个月，总体术后超重减轻率为78.1%（标准差，14.3%）。术前未记录体重减轻情况。显示出与外科医生相关的学习曲线，手术时间以及与手术相关的并发症有所减少。肥胖相关的合并症减少，而生活质量提高。
尽管术前采用了结构化的多学科方法来改变生活方式和每日热量摄入，但只有腹腔镜Roux-en-Y胃旁路手术显示出有效的体重减轻并减少了相关合并症。
