[促肾上腺皮质激素对肌肉功能和代谢过程的影响]
[Effect of corticotropin on functional and metabolic processes in muscles].
作者信息
Korkach V I
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1977 Jun;63(6):852-7.
Changes of excitability, contractility, temperature, activity of oxydation-reduction enzymes, pyridine nucleotides, and of free fatty acids were studied in m. m. gastrocnemii of rabbits and rats during activity, after administration of 1 unit per 100 g of corticotropin (ACTH). Within 30 min after administration, the ACTH did not alter the excitability of a neural-muscular system but increased its efficiency by means of stimulation of the free fatty acids usage. Besides, the ACTH elicits no regular changes of the oxydation--reduction enzymes activity during a short-lasting muscular activity. Its regulating effect on the metabolic processes in muscles is realised at the level of anaerobic processes.
在给家兔和大鼠每100克体重注射1单位促肾上腺皮质激素（ACTH）后，研究了其腓肠肌在活动期间兴奋性、收缩性、温度、氧化还原酶活性、吡啶核苷酸和游离脂肪酸的变化。给药后30分钟内，ACTH未改变神经肌肉系统的兴奋性，但通过刺激游离脂肪酸的利用提高了其效率。此外，在短暂的肌肉活动期间，ACTH不会引起氧化还原酶活性的规律性变化。其对肌肉代谢过程的调节作用是在无氧过程水平上实现的。
Zotero 插件