Dunlap Brian S, Bailes James R
Department of Pediatrics and Pediatric Endocrinology, Marshall University, Huntington, WV 25701, USA.
Metab Syndr Relat Disord. 2008 Mar;6(1):32-6. doi: 10.1089/met.2007.0023.
Childhood obesity is a leading health concern. We have previously demonstrated the effectiveness of a restricted-carbohydrate, unlimited energy diet for weight reduction in elementary school-aged children. To our knowledge, there are no studies that have looked at the effect of this diet on lipid profiles in elementary school-aged children. Therefore, the objective of this pilot study was to examine the effect of a restricted-carbohydrate, unlimited protein, unlimited energy diet on lipid profiles in obese children 6 to 12 years of age.
Overweight children (body mass index >97%) referred to our obesity clinic were treated with a restricted-carbohydrate (<30 grams daily), unlimited protein, and unlimited energy diet. Weight, height, body mass index, and fasting lipid profiles were obtained at baseline and at 10 weeks on each patient.
Twenty-seven patients were enrolled in our study, with a total of 18 patients returning for our 10 week follow-up (67%). The study group included 10 males and 8 females, with an age range of 6 to 12 years. Both total serum cholesterol and triglyceride levels showed a significant reduction; 24.2 (P = 0.018) and 56.9 (P = 0.015) mg/dL, respectively.
We have demonstrated a significant decrease in total cholesterol and triglycerides in elementary school-aged children after 10 weeks of a restricted-carbohydrate, unlimited protein, and unlimited energy diet. We suggest that this diet may decrease cardiovascular risk factors in obese children. Long-term studies will be needed to substantiate these data.
儿童肥胖是一个主要的健康问题。我们之前已经证明了一种碳水化合物受限、能量不限的饮食对小学年龄段儿童减重的有效性。据我们所知,尚无研究探讨这种饮食对小学年龄段儿童血脂谱的影响。因此,这项初步研究的目的是检验碳水化合物受限、蛋白质不限、能量不限的饮食对6至12岁肥胖儿童血脂谱的影响。
被转诊至我们肥胖门诊的超重儿童(体重指数>97%)接受碳水化合物受限(每日<30克)、蛋白质不限、能量不限的饮食治疗。在基线和每位患者10周时获取体重、身高、体重指数和空腹血脂谱。
27名患者纳入我们的研究,共有18名患者返回进行10周的随访(67%)。研究组包括10名男性和8名女性,年龄范围为6至12岁。血清总胆固醇和甘油三酯水平均显著降低;分别降低了24.2(P = 0.018)和56.9(P = 0.015)mg/dL。
我们已经证明,在进行10周的碳水化合物受限、蛋白质不限、能量不限的饮食后,小学年龄段儿童的总胆固醇和甘油三酯显著降低。我们认为这种饮食可能会降低肥胖儿童的心血管危险因素。需要长期研究来证实这些数据。