乘势而上：间充质干细胞的神经和非神经起源

Riding the waves: neural and nonneural origins for mesenchymal stem cells.

作者信息

Miller Freda D

机构信息

Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON M5G 1L7, Canada.

出版信息

Cell Stem Cell. 2007 Aug 16;1(2):129-30. doi: 10.1016/j.stem.2007.07.007.

DOI:10.1016/j.stem.2007.07.007

PMID:18371342

Abstract

The role of endogenous mesenchymal stem cells (MSCs) is enigmatic. Recently in Cell, Takashima et al. (2007) addressed the biological origin of MSCs and showed that they are generated in waves, with the neuroepithelium unexpectedly providing the first wave and a second wave of nonneural-derived MSCs taking precedence in the adult.

摘要

内源性间充质干细胞（MSC）的作用尚不明确。最近，高岛等人（2007年）在《细胞》杂志上探讨了MSC的生物学起源，结果表明它们呈波浪式产生，其中神经上皮意外地提供了第一波，而第二波非神经来源的MSC在成体中占主导地位。