Rehring Thomas F, Stolcpart Ryan S, Hollis H Whitton
Division of Vascular and Endovascular Surgery, Department of Vascular Therapy, Colorado Permanente Medical Group, Denver, CO 80205, USA.
J Vasc Surg. 2008 May;47(5):1108-15. doi: 10.1016/j.jvs.2007.12.033. Epub 2008 Apr 18.
There is broad and compelling evidence for risk factor reduction to limit cardiovascular morbidity and mortality in patients with peripheral arterial disease. Indeed, vascular surgeons have placed a call to arms to ensure this takes place. Despite this fact, some wariness exists on the part of many vascular surgeons to initiate these strategies, functionally abnegating their responsibilities in this regard. The purpose of this article is to provide a simple reference to guide effective therapies for overall cardiovascular risk reduction in patients with peripheral arterial disease. Specific recommendations are made for tobacco cessation, lipid-lowering therapy, antiplatelet therapy, blood pressure control, and maintenance of normoglycemia.
有广泛且令人信服的证据表明，降低危险因素可减少外周动脉疾病患者的心血管发病率和死亡率。事实上，血管外科医生已发出行动呼吁，以确保这一目标得以实现。尽管如此，许多血管外科医生在启动这些策略时仍存在一些顾虑，实际上在这方面放弃了他们的责任。本文的目的是提供一个简单的参考，以指导有效治疗外周动脉疾病患者以降低整体心血管风险。针对戒烟、降脂治疗、抗血小板治疗、血压控制和维持血糖正常提出了具体建议。
