Larm Peter, Hodgins Sheilagh, Larsson Agne, Samuelson Yasmina Molero, Tengström Anders
Research Centre for Adolescents Psycho-social Health, Section of Alcohol & Drug Dependence Research, Department of Clinical Neuroscience, Karolinska Institutet, S:t Göran's Hospital, Box 500, 112 81 Stockholm, Sweden.
Drug Alcohol Depend. 2008 Jul 1;96(1-2):79-89. doi: 10.1016/j.drugalcdep.2008.01.026. Epub 2008 Mar 28.
Little is known about the long-term outcome of substance misuse by teenagers, this is especially true for gender specific consequences.
To examine the prevalence of death, physical illnesses related to substance misuse, mental illness, substance misuse, criminality, and poverty in adulthood among two cohorts of individuals who as adolescents had consulted for substance misuse problems, to estimate the effect of sex on adverse outcomes, and to compare cohort effects.
Individuals who had consulted a substance misuse clinic as adolescents during 1968-1971 and 1980-1984 were followed until 2002. Adverse outcomes were documented using information from Swedish national registers.
In the older cohort followed to age 50, only one-in-five escaped all six adverse outcomes, while over half of subjects experienced at least two or more. Sex and the severity of adolescent substance misuse and delinquency were predictors of adverse outcomes. More women than men experienced physical illness and poverty in the older cohort while more men than women were convicted of criminal offences in both cohorts and presented continued substance misuse in the younger cohort. Men in the younger as compared to the older cohort had higher rates of substance misuse and criminal convictions.
Adolescents seeking help for substance misuse problems are at elevated risk for multiple adverse outcomes later in life. Outcomes differ for women and men and by severity of adolescent misuse and delinquency. Few cohort differences in adult outcomes exist.
对于青少年药物滥用的长期后果,我们知之甚少,尤其是其特定性别的后果。
调查两组曾在青少年时期因药物滥用问题前来咨询的人群在成年后死亡、与药物滥用相关的身体疾病、精神疾病、药物滥用、犯罪及贫困的发生率,评估性别对不良后果的影响,并比较队列效应。
对1968 - 1971年及1980 - 1984年期间在青少年时期曾咨询过药物滥用诊所的个体进行随访,直至2002年。使用瑞典国家登记处的信息记录不良后果。
在随访至50岁的年长队列中,只有五分之一的人避免了所有六种不良后果,而超过一半的受试者经历了至少两种或更多不良后果。性别、青少年药物滥用和犯罪的严重程度是不良后果的预测因素。在年长队列中,经历身体疾病和贫困的女性多于男性,而在两个队列中,被判定有罪的男性多于女性,并且在年轻队列中,持续存在药物滥用问题的男性也多于女性。与年长队列相比,年轻队列中的男性药物滥用率和犯罪定罪率更高。
因药物滥用问题寻求帮助的青少年在日后生活中面临多种不良后果的风险更高。女性和男性的后果不同,且因青少年滥用和犯罪的严重程度而异。成年后的结果在队列之间几乎没有差异。