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CompariMotif:序列基序的快速简便比较。

CompariMotif: quick and easy comparisons of sequence motifs.

作者信息

Edwards Richard J, Davey Norman E, Shields Denis C

机构信息

UCD Complex and Adaptive Systems Laboratory and UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Dublin 4, Ireland.

出版信息

Bioinformatics. 2008 May 15;24(10):1307-9. doi: 10.1093/bioinformatics/btn105. Epub 2008 Mar 28.

Abstract

UNLABELLED

CompariMotif is a novel tool for making motif-motif comparisons, identifying and describing similarities between regular expression motifs. CompariMotif can identify a number of different relationships between motifs, including exact matches, variants of degenerate motifs and complex overlapping motifs. Motif relationships are scored using shared information content, allowing the best matches to be easily identified in large comparisons. Many input and search options are available, enabling a list of motifs to be compared to itself (to identify recurring motifs) or to datasets of known motifs.

AVAILABILITY

CompariMotif can be run online at http://bioware.ucd.ie/ and is freely available for academic use as a set of open source Python modules under a GNU General Public License from http://bioinformatics.ucd.ie/shields/software/comparimotif/

摘要

未标记

CompariMotif是一种用于进行基序-基序比较、识别和描述正则表达式基序之间相似性的新型工具。CompariMotif可以识别基序之间的多种不同关系,包括精确匹配、简并基序的变体和复杂的重叠基序。使用共享信息内容对基序关系进行评分,从而在大型比较中轻松识别最佳匹配。提供了许多输入和搜索选项,使一组基序能够与自身(以识别重复出现的基序)或已知基序数据集进行比较。

可用性

CompariMotif可在http://bioware.ucd.ie/上在线运行,并且作为一组开源Python模块,根据GNU通用公共许可证,可从http://bioinformatics.ucd.ie/shields/software/comparimotif/免费用于学术用途。

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