Bucher Pascal, Pugin Francois, Morel Philippe
Department of Surgery, Clinic of Visceral and Transplantation Surgery, Geneva University Hospital, Geneva, Switzerland.
Pancreas. 2008 Mar;36(2):113-9. doi: 10.1097/MPA.0b013e3181514c9e.
Infected necrotizing pancreatitis represents a serious and therapeutically challenging complication. Percutaneous drainage of infected pancreatic necrosis is often unsuccessful. Alternatively, open necrosectomies are associated with high morbidity. Recently, minimally invasive necrosectomy techniques have been tried with satisfying results; however, they frequently necessitate multiple sessions for definitive necrosectomy. To evaluate results of single large-port laparoscopic necrosectomy for proven infected necrotizing pancreatitis.
Eight patients presenting proven infected pancreatic necrosis during course of acute pancreatitis and not responding to radiological drainage were prospectively offered minimally invasive necrosectomy. Laparoscopic necrosectomy were performed using a single large port placed along the drain tract directly into the infected necrosis. In all patients, drainage was placed during laparoscopic necrosectomy for continuous postoperative lavage.
No perioperative complications were recorded with a median operative time of 87 +/- 42 minutes. No blood transfusions were needed. No surgical postoperative morbidity and mortality were recorded. In all cases, except for one patient with multiple abscesses, only one session of necrosectomy was sufficient to completely clear the necrotic abscess. Laparoscopic necrosectomy was successful in all patients, and none required complementary surgical or radiological treatment.
Minimally invasive necrosectomy has been safe and highly efficient through single large-port laparoscopy for infected pancreatic necrosis in our series of patients. Minimally invasive necrosectomy is a promising technique for infected necrotizing pancreatitis and should be regarded as a valid therapeutic option for necrotizing pancreatitis.
感染性坏死性胰腺炎是一种严重且治疗具有挑战性的并发症。经皮引流感染性胰腺坏死往往不成功。另外,开放性坏死组织清除术的发病率较高。最近,尝试了微创坏死组织清除术,结果令人满意;然而,它们通常需要多次手术才能完成确定性坏死组织清除术。评估单孔大口径腹腔镜坏死组织清除术治疗确诊的感染性坏死性胰腺炎的效果。
前瞻性地为8例在急性胰腺炎病程中出现确诊的感染性胰腺坏死且对放射学引流无反应的患者提供微创坏死组织清除术。腹腔镜坏死组织清除术通过沿引流管放置的单个大端口直接进入感染性坏死组织进行。所有患者在腹腔镜坏死组织清除术期间均放置引流管以进行术后持续灌洗。
未记录围手术期并发症,中位手术时间为87±42分钟。无需输血。未记录手术术后发病率和死亡率。在所有病例中,除1例有多发性脓肿的患者外,仅一次坏死组织清除术就足以完全清除坏死性脓肿。腹腔镜坏死组织清除术在所有患者中均成功,无一例需要辅助手术或放射学治疗。
在我们的一系列患者中,通过单孔大口径腹腔镜进行微创坏死组织清除术治疗感染性胰腺坏死是安全且高效的。微创坏死组织清除术是治疗感染性坏死性胰腺炎的一种有前景的技术,应被视为坏死性胰腺炎的一种有效治疗选择。