分裂型相关强迫症的临床特征
Clinical characteristics of schizotypal-related obsessive-compulsive disorder.
作者信息
Poyurovsky Michael, Faragian Sarit, Pashinian Artashez, Heidrach Lilah, Fuchs Camil, Weizman Ronit, Koran Lorrin
机构信息
Research Unit, Tirat Carmel Mental Health Center, Tirat Carmel, Israel.
出版信息
Psychiatry Res. 2008 May 30;159(1-2):254-8. doi: 10.1016/j.psychres.2007.02.019. Epub 2008 Apr 18.
In this study we compared 15 patients with DSM-IV obsessive-compulsive disorder (OCD) and schizotypal personality disorder (SPD) and 31 non-SPD OCD patients. OCD-SPD patients had poorer insight, more negative symptoms, lower functioning, more antipsychotic augmentation and more first-degree relatives with schizophrenia-spectrum disorders. A distinct clinical phenotype of OCD associated with SPD should be considered when investigating etiopathogenetic mechanisms.
在本研究中，我们比较了15例患有DSM-IV强迫症（OCD）和分裂型人格障碍（SPD）的患者以及31例非SPD的OCD患者。OCD-SPD患者的自知力较差、阴性症状较多、功能较低、抗精神病药物增效治疗较多，且有精神分裂症谱系障碍的一级亲属较多。在研究病因发病机制时，应考虑与SPD相关的OCD的独特临床表型。
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