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老年精神分裂症患者的强迫症

Obsessive-compulsive disorder in elderly schizophrenia patients.

作者信息

Poyurovsky Michael, Bergman Josef, Weizman Ronit

机构信息

Research Unit, Tirat Carmel Mental Health Center, 9 Eshkol St., Tirat Carmel 30200, Israel.

出版信息

J Psychiatr Res. 2006 Apr;40(3):189-91. doi: 10.1016/j.jpsychires.2005.03.009.

Abstract

Obsessive-compulsive disorder (OCD) has been identified in a substantial proportion of adult schizophrenia patients. Although symptoms of both disorders may persist into senescence, the prevalence of OCD in elderly schizophrenia patients has not yet been explicitly evaluated. We evaluated the prevalence of OCD in 50 elderly patients consecutively hospitalized for acute exacerbation of DSM-IV schizophrenia or schizoaffective disorder. The severity of schizophrenia and OCD symptoms was assessed using appropriate clinical rating scales. Eight (16%) of the 50 participants also met DSM-IV criteria for OCD. Schizophrenia patients with and without OCD did not differ significantly in demographic and clinical variables. In half of the schizophrenia-OCD group late onset OCD was observed, while in the remaining schizophrenia-OCD patients, early-onset OCD persisted into senescence, suggesting distinct mechanisms of occurrence. We conclude that OCD is not rare in elderly schizophrenia patients. Identification of this potentially treatable condition is imperative to provide adequate care.

摘要

相当一部分成年精神分裂症患者存在强迫症(OCD)。尽管这两种疾病的症状可能会持续到老年,但老年精神分裂症患者中强迫症的患病率尚未得到明确评估。我们评估了50名因DSM-IV精神分裂症或精神分裂情感障碍急性加重而连续住院的老年患者中强迫症的患病率。使用适当的临床评定量表评估精神分裂症和强迫症症状的严重程度。50名参与者中有8名(16%)也符合DSM-IV强迫症标准。有强迫症和无强迫症的精神分裂症患者在人口统计学和临床变量方面无显著差异。在一半的精神分裂症-强迫症组中观察到迟发性强迫症,而在其余的精神分裂症-强迫症患者中,早发性强迫症持续到老年,提示发病机制不同。我们得出结论,强迫症在老年精神分裂症患者中并不罕见。识别这种潜在可治疗的疾病对于提供充分的治疗至关重要。

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