Subak Leslee L, Brubaker Linda, Chai Toby C, Creasman Jennifer M, Diokno Ananias C, Goode Patricia S, Kraus Stephen R, Kusek John W, Leng Wendy W, Lukacz Emily S, Norton Peggy, Tennstedt Sharon
Department of Obstetrics, Gynecology & Reproductive Sciences and Epidemiology & Biostatistics, University of California, San Francisco, California, USA.
Obstet Gynecol. 2008 Apr;111(4):899-907. doi: 10.1097/AOG.0b013e31816a1e12.
To estimate costs for incontinence management, health-related quality of life, and willingness to pay for incontinence improvement in women electing surgery for stress urinary incontinence.
A total of 655 incontinent women enrolled in the Stress Incontinence Surgical Treatment Efficacy Trial, a randomized surgical trial. Baseline out-of-pocket costs for incontinence management were calculated by multiplying self-report of resources used (supplies, laundry, dry cleaning) by national resource costs (USD2,006). Health-related quality of life was estimated with the Health Utilities Index Mark 3. Participants estimated willingness to pay for 100% improvement in incontinence. Potential predictors of these outcomes were examined by using multivariable linear regression.
Mean age was 52+/-10 years, and mean number of weekly incontinence episodes was 22+/-21. Mean and median (25%, 75% interquartile range) estimated personal costs for incontinence management among all women were USD14+/-USD24 and USD8 (interquartile range USD3, USD18) per week, and 617 (94%) women reported any cost. Costs increased significantly with incontinence frequency and mixed compared with stress incontinence. The mean and median Health Utilities Index Mark 3 scores were 0.73+/-0.25 and 0.84 (interquartile range 0.63, 0.92). Women were willing to pay a mean of USD118+/-USD132 per month for complete resolution of incontinence, and willingness to pay increased significantly with greater expected incontinence improvement, household income, and incontinent episode frequency.
Urinary incontinence is associated with substantial costs. Women spent nearly USD750 per year out of pocket for incontinence management, had a significant decrement in quality of life, and were willing to pay nearly USD1,400 per year for cure.
评估为压力性尿失禁选择手术治疗的女性在尿失禁管理方面的费用、健康相关生活质量以及为改善尿失禁状况的支付意愿。
共有655名尿失禁女性参与了压力性尿失禁手术治疗疗效试验,这是一项随机手术试验。通过将所使用资源(用品、洗衣、干洗)的自我报告乘以国家资源成本(2006美元)来计算尿失禁管理的基线自付费用。使用健康效用指数Mark 3评估健康相关生活质量。参与者估计为使尿失禁状况改善100%的支付意愿。通过多变量线性回归分析这些结果的潜在预测因素。
平均年龄为52±10岁,每周尿失禁发作的平均次数为22±21次。所有女性中尿失禁管理的估计个人平均费用和中位数(第25百分位数,第75百分位数四分位间距)分别为每周14±24美元和8美元(四分位间距3美元,18美元),617名(94%)女性报告有任何费用。费用随尿失禁频率显著增加,且混合性尿失禁与压力性尿失禁相比费用更高。健康效用指数Mark 3的平均得分和中位数得分分别为0.73±0.25和0.84(四分位间距0.63,0.92)。女性为完全解决尿失禁问题每月平均愿意支付118±132美元,支付意愿随预期尿失禁改善程度、家庭收入和尿失禁发作频率的增加而显著增加。
尿失禁与大量费用相关。女性每年为尿失禁管理自掏腰包近750美元,生活质量显著下降,并且每年愿意支付近1400美元用于治愈尿失禁。