Price Molly Daymont, Shulman Lisa M
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Menopause Int. 2008 Mar;14(1):38-9. doi: 10.1258/mi.2007.007038.
Elderly women with Parkinson's disease (PD) represent a specific patient population that may benefit from individualized treatment strategies. PD has been shown to occur approximately twice as often in men than in women, resulting in theories regarding estrogen being protective against the disease and as a potential treatment strategy. Given women's longer life expectancy, they are more likely to reach an age where antiparkinsonian medications are associated with side-effects. This paper will review medical and surgical treatments as well as the relationship of gender and age with respect to the management of PD.
患有帕金森病(PD)的老年女性是一个特殊的患者群体,可能会从个体化治疗策略中受益。帕金森病在男性中的发病率约为女性的两倍,由此产生了关于雌激素对该疾病具有保护作用以及作为一种潜在治疗策略的理论。鉴于女性预期寿命更长,她们更有可能达到抗帕金森病药物会产生副作用的年龄。本文将综述药物和手术治疗,以及性别和年龄与帕金森病管理的关系。