Humphrey T J, Baskerville A, Chart H, Rowe B, Whitehead A
Public Health Laboratory, Exeter.
Vet Rec. 1991 Nov 30;129(22):482-5. doi: 10.1136/vr.129.22.482.
The period during which specific pathogen free hens, infected by direct introduction into the crop of either 10(3), 10(6) or 10(8) cells of Salmonella enteritidis PT4, excreted the organism in faeces was closely related to the size of the inoculum, with the birds excreting for mean periods of 3.4, 16.4 and 36.8 days, respectively. The production of either IgG or IgM was also dose related with the birds which received 10(3) cells having lower antibody levels than those in the other two groups. In contrast, there was no relationship between the contamination of egg contents and either antibody status, faecal excretion, or the dose administered.
将肠炎沙门氏菌PT4的10³、10⁶或10⁸个细胞直接接种到特定病原体-free母鸡的嗉囊中,这些母鸡粪便中排出该病原体的时期与接种量密切相关,母鸡排出病原体的平均时期分别为3.4天、16.4天和36.8天。IgG或IgM的产生也与剂量相关,接受10³个细胞的母鸡抗体水平低于其他两组。相比之下,蛋内容物的污染与抗体状态、粪便排泄或给药剂量之间没有关系。