Dalgiç Ali, Seçer Mehmet, Ergüngör Fikret, Okay Onder, Akdağ Rifat, Ciliz Deniz
Ankara Numune Educational and Training Hospital, II. Neurosurgery Clinic, Ankara, Turkey.
Turk Neurosurg. 2008 Jan;18(1):70-7.
Dural sinus thrombosis (DST) usually involves the sagittal, transverse and sigmoid sinuses and is more common in women due to pregnancy, puerperium and oral contraceptive use. Other etiologies include coagulopathies, infection and head injury. We have present two DST cases following head injury. The first case was a 35-year-old man hospitalized because of one-week history of headache and repeated vomiting after a mild head injury. Thrombosis of the superior sagittal sinus, right transverse and sigmoid sinuses and right jugular vein was determined on angiography. The second case was a 25- year-old man operated on for epidural hematoma at the posterior fossa. Meningitis developed and an abducens palsy was determined. Magnetic resonance imaging demonstrated thrombosis of the right transverse and sigmoid sinus. Low molecular weight heparin was administrated for three months. Both cases had good recovery, but one had recanalisation of the thrombosis. Intracranial hematomas, depressed skull fracture or skull fracture that cross the sinus can obstruct the blood flow in the sinus. Moreover, closed head injury may cause to DST. Because of undefinitive pathophysiology, a consensus was not obtained on overall strategy concerning conservative, radiosurgical, or surgical therapy yet.
硬脑膜窦血栓形成(DST)通常累及矢状窦、横窦和乙状窦,由于妊娠、产褥期和使用口服避孕药,在女性中更为常见。其他病因包括凝血障碍、感染和头部损伤。我们报告了两例头部损伤后发生的DST病例。第一例是一名35岁男性,因轻度头部损伤后有一周的头痛和反复呕吐病史而住院。血管造影显示上矢状窦、右侧横窦和乙状窦以及右侧颈静脉血栓形成。第二例是一名25岁男性,因后颅窝硬膜外血肿接受手术。发生了脑膜炎并确定有外展神经麻痹。磁共振成像显示右侧横窦和乙状窦血栓形成。给予低分子量肝素治疗三个月。两例患者均恢复良好,但其中一例血栓再通。颅内血肿、颅骨凹陷骨折或跨越窦的颅骨骨折可阻碍窦内血流。此外,闭合性头部损伤可能导致DST。由于病理生理学尚不明确,关于保守治疗、放射外科治疗或手术治疗的总体策略尚未达成共识。