Charvát J, Kratochvíl J, Martínková V, Masopust J, Pálová S
Interní klinika 2. LF UK a FNM, Praha.
Cas Lek Cesk. 2008;147(2):106-11.
Early enteral nutrition is recommended in patients with critical illness. Generally implementing of nutritional support algorithm is advised. The aim of study was evaluation of early enteral nutrition application in critically ill patients in medical intensive care unit.
Early enteral nutrition was given according to written protocol in medical intensive care unit. During the first 96 hours hypocaloric nutrition 20-25 calories/kg was applied, followed by increase to 25-30 calories/kg at the end of the first week of admission. Apart from the patients who reached 25-30 calories/kg we recorded the number of patients who tolerated hypocaloric enteral nutrition and evaluated the number of patients with complications due to enteral nutrition. Early enteral nutrition was given to 44 out of 99 patients admitted to intensive care unit with life threatening diasese and indication for nutrition support. Out of 44 critically ill patients (35 with sepsis, 9 with another medical emergency) 22 died during admisssion in intensive care unit (50%). Hypocaloric enteral nutrition during the first 96 hours was given to 36 patients (82%). In 8 patients enteral nutrition had to be stopped and substituted for parenteral one due to complications. Three patients suffered from abdominal distension, 2 from profused diarrhea, 1 from combination of diarrhea and abdominal distension and 2 from aspiration. Twenty seven patients tolerated the application of enteral nutrition via nasogastric tube. In 10 patients nasogastric tube had to be replaced for nasojejunal one for high gastric aspirate volume. The caloric intake of 25-30 calories/kg was reached by the end of the first week of admission in 26 patients (60%).
Early enteral nutrition applied according to protocol was given succesfully to the substantial number of the critical patients. In 18% of the patients enteral nutrition had to be replaced for parenteral one due to complications. The caloric intake 25-30 calories/kg was reached in 60% of patients.
重症患者推荐早期肠内营养。一般建议实施营养支持算法。本研究的目的是评估医学重症监护病房中重症患者早期肠内营养的应用情况。
在医学重症监护病房,按照书面方案给予早期肠内营养。在最初的96小时内给予低热量营养,即20 - 25千卡/千克,入院第一周结束时增加至25 - 30千卡/千克。除了达到25 - 30千卡/千克的患者外,我们记录了耐受低热量肠内营养的患者数量,并评估了因肠内营养出现并发症的患者数量。99名因危及生命的疾病入住重症监护病房且有营养支持指征的患者中,44名接受了早期肠内营养。在这44名重症患者中(35名患有脓毒症,9名患有其他内科急症),22名在重症监护病房住院期间死亡(50%)。36名患者(82%)在最初的96小时内接受了低热量肠内营养。8名患者因并发症不得不停止肠内营养并改用肠外营养。3名患者出现腹胀,2名出现大量腹泻,1名出现腹泻和腹胀的组合,2名出现误吸。27名患者耐受经鼻胃管给予的肠内营养。10名患者因胃吸出量高,鼻胃管不得不更换为鼻空肠管。26名患者(60%)在入院第一周结束时达到了25 - 30千卡/千克的热量摄入。
按照方案应用的早期肠内营养成功给予了大量重症患者。18%的患者因并发症不得不将肠内营养更换为肠外营养。60%的患者达到了25 - 30千卡/千克的热量摄入。