Rice Todd W, Swope Teresa, Bozeman Susan, Wheeler Arthur P
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Nutrition. 2005 Jul-Aug;21(7-8):786-92. doi: 10.1016/j.nut.2004.11.014.
We determined the variability in enteral feeding practices in mechanically ventilated patients in four adult intensive care units of a tertiary-care, referral hospital.
Patients who had been mechanically ventilated for at least 48 h and received enteral nutrition were prospectively followed.
Fifty-five of 101 consecutive mechanically ventilated patients received enteral nutrition; in 93% of patients, feedings were infused into the stomach. Patients who were cared for in the medical intensive care unit, where a nutritional protocol was operational, received enteral nutrition earlier in their ventilatory course (P=0.004) and feedings were advanced to target rates faster (P=0.043) than those who received care in other units. The number (P=0.243) and duration (P=0.668) of interruptions in feeding did not differ by patient location. On average, patients received only 50% to 70% of their targeted caloric goals during the first 6 days of enteral nutrition. Most feeding discontinuations (41%) were secondary to procedures. Gastrointestinal intolerances, including vomiting, aspiration, abdominal distention, and increased gastric residuals, were uncommon despite allowing gastric residuals up to 300 mL.
The practice of providing enteral feeds to mechanically ventilated patients varies widely, even within one hospital. A protocol enhanced early initiation of enteral feeds and advancement to target feeding rates but did not alter the number or duration of interruptions in enteral feedings. Procedures represented the most common reason for stopping enteral feeds, and gastrointestinal intolerances (vomiting, aspiration, and increased gastric residuals) caused few feeding interruptions. The gastric route was safe and well tolerated for early enteral feeding in most mechanically ventilated patients.
我们确定了一家三级转诊医院的四个成人重症监护病房中机械通气患者肠内喂养方式的变异性。
对机械通气至少48小时并接受肠内营养的患者进行前瞻性随访。
101例连续机械通气患者中有55例接受了肠内营养;93%的患者通过胃内输注进行喂养。在实施营养方案的内科重症监护病房接受治疗的患者,在通气过程中更早开始接受肠内营养(P = 0.004),且喂养量提升至目标速率的速度更快(P = 0.043),这优于在其他病房接受治疗的患者。喂养中断的次数(P = 0.243)和持续时间(P = 0.668)在不同病房的患者中无差异。在肠内营养的前6天,患者平均仅达到其目标热量摄入的50%至70%。大多数喂养中断(41%)继发于操作。尽管允许胃残余量达300 mL,但包括呕吐、误吸、腹胀和胃残余量增加在内的胃肠道不耐受情况并不常见。
即使在同一家医院内,为机械通气患者提供肠内喂养的方式也存在很大差异。一项方案促进了肠内喂养的早期启动和向目标喂养速率的推进,但并未改变肠内喂养中断的次数或持续时间。操作是停止肠内喂养的最常见原因,胃肠道不耐受(呕吐、误吸和胃残余量增加)导致的喂养中断很少。在大多数机械通气患者中,胃途径用于早期肠内喂养是安全且耐受性良好的。