Yamaguchi T, Blackall P J, Takigami S, Iritani Y, Hayashi Y
Aburahi Laboratories, Shionogi & Co., Shiga, Japan.
Avian Dis. 1991 Oct-Dec;35(4):965-8.
Immunogenicity of three Haemophilus paragallinarum serovar B strains was investigated in cross-protection tests using monovalent vaccines prepared from the B strains, as well as one strain each of serovars A and C. A bivalent vaccine composed of the serovar A and C strains also was used. In the studies with the monovalent vaccines, the immunogenicity of serovar B strains was different from that of serovar A and C strains, although only partial serovar B-specific protection with the three strains was observed. Chickens vaccinated with the bivalent vaccine protected against challenge with one serovar B strain, as well as serovar A and C strains, but not against the other two serovar B strains.
使用从B型菌株制备的单价疫苗以及A型和C型菌株各一株，在交叉保护试验中研究了三株副鸡嗜血杆菌B型菌株的免疫原性。还使用了由A型和C型菌株组成的二价疫苗。在单价疫苗的研究中，B型菌株的免疫原性与A型和C型菌株不同，尽管仅观察到三株菌株具有部分B型特异性保护作用。用二价疫苗接种的鸡对一株B型菌株以及A型和C型菌株的攻击具有保护作用，但对另外两株B型菌株没有保护作用。
