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CREST综合征相关的多发性颅内动脉瘤和双侧视神经病变。

CREST-associated multiple intracranial aneurysms and bilateral optic neuropathies.

作者信息

Ortiz J R, Newman N J, Barrow D L

机构信息

Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.

出版信息

J Clin Neuroophthalmol. 1991 Dec;11(4):233-40.

PMID:1838540
Abstract

A patient with a clinical and serological diagnosis of CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal motility abnormalities, sclerodactyly, telangiectatic lesions), a variant of PSS (progressive systemic sclerosis), was found to have multiple intracranial aneurysms. She subsequently developed bilateral optic neuropathies. Ischemic and compressive etiologies are proposed and related to the histopathology of the patient's underlying systemic disease.

摘要

一名临床和血清学诊断为CREST综合征(钙质沉着、雷诺现象、食管运动异常、指端硬化、毛细血管扩张性病变)的患者,这是进行性系统性硬化症(PSS)的一种变体,被发现患有多个颅内动脉瘤。她随后出现双侧视神经病变。提出了缺血性和压迫性病因,并与该患者潜在全身性疾病的组织病理学相关。

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