抗抑郁药：新的作用机制能否改善不良疗效？

Antidepressants: will new mechanisms of action improve poor outcomes?

作者信息

Palaniyappan Lena, McAllister-Williams R Hamish

机构信息

Institute of Neuroscience, Newcastle University, Royal Victoria Infirmary, Newcastle upon Tyne.

出版信息

Br J Hosp Med (Lond). 2008 Feb;69(2):88-90. doi: 10.12968/hmed.2008.69.2.28353.

DOI:10.12968/hmed.2008.69.2.28353

PMID:18386732

Abstract

Depression is one of the most common mental illnesses and has a high impact on individuals and society. Despite the numerous treatment approaches, poor response combined with the burden of residual symptoms negatively affects the overall outcome. Novel pharmacological approaches could help to address this issue.

摘要

抑郁症是最常见的精神疾病之一，对个人和社会都有很大影响。尽管有多种治疗方法，但疗效不佳以及残留症状的负担对总体治疗结果产生了负面影响。新的药理学方法可能有助于解决这一问题。