Lilleeng Bård, Helseth Eirik
Nevrokirurgisk avdeling, Nevroklinikken, Rikshospitalet, Oslo.
Tidsskr Nor Laegeforen. 2008 Apr 3;128(7):818-21.
Meningioma is one of the most common primary intraspinal tumours in adults. Most patients with this condition develop myelopathy or radiculopathy. The treatment of choice for these tumours is surgery, although few data are published on neurological outcome after surgery for intraspinal meningiomas. Patients are increasingly asking about the prognosis before they consent to surgery. This study aims at investigating operative morbidity and neurological outcome in a continuous surgical series in Norway.
The material comprised all 28 patients treated for histologically verified intraspinal meningioma at Rikshospitalet in the time period 1999 to 2003. All patients underwent new radiological and clinical assessments for study purposes.
We found that 96.5% of the patients were neurologically improved or unchanged after surgery. There was no recurrence, nor mortality. These findings match earlier reports in the literature. Morbidity was at 18%, this was higher than in other studies due to our wide definition of surgical morbidity. We conclude that surgery can be performed with excellent outcome, whilst the morbidity and mortality remain low.
脑膜瘤是成人最常见的原发性椎管内肿瘤之一。大多数患有这种疾病的患者会出现脊髓病或神经根病。这些肿瘤的首选治疗方法是手术,尽管关于椎管内脑膜瘤手术后神经功能转归的 published 数据很少。患者在同意手术前越来越多地询问预后情况。本研究旨在调查挪威一个连续手术系列中的手术并发症和神经功能转归。
材料包括1999年至2003年期间在Rikshospitalet接受组织学证实的椎管内脑膜瘤治疗的所有28例患者。为研究目的,所有患者均接受了新的影像学和临床评估。
我们发现96.5%的患者术后神经功能得到改善或未改变。无复发及死亡情况。这些发现与文献中早期报道相符。并发症发生率为18%,由于我们对手术并发症的宽泛定义,该发生率高于其他研究。我们得出结论,手术可取得良好效果,同时并发症和死亡率仍然较低。